دورية أكاديمية
Impact of response shift effects in the assessment of selfreported depression during treatment: insights from a rTMS versus Venlafaxine randomized controlled trial
| العنوان: | Impact of response shift effects in the assessment of selfreported depression during treatment: insights from a rTMS versus Venlafaxine randomized controlled trial |
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| المؤلفون: | Bulteau, Samuel, Blanchin, Myriam, Pere, Morgane, Poulet, Emmanuel, Brunelin, Jérôme, Sauvaget, Anne, Sébille, Véronique |
| المساهمون: | MethodS in Patients-centered outcomes and HEalth ResEarch (SPHERE), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Nantes Université - UFR des Sciences Pharmaceutiques et Biologiques (Nantes Univ - UFR Pharmacie), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Department of Addictology and Psychiatry Nantes, Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes), Biostatistics and Methodology Unit Nantes, Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center (CRNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Service des urgences psychiatriques Lyon, Hôpital Edouard Herriot CHU - HCL, Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL) |
| المصدر: | ISSN: 0022-3956. |
| بيانات النشر: | HAL CCSD Elsevier |
| سنة النشر: | 2023 |
| المجموعة: | HAL Lyon 1 (University Claude Bernard Lyon 1) |
| مصطلحات موضوعية: | Response Shift, Depression, rTMS, venlafaxine, Patient-Reported Outcomes, [SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health, [STAT.AP]Statistics [stat]/Applications [stat.AP] |
| الوصف: | International audience ; Patient-Reported Outcomes are essential to properly assess treatment effectiveness in randomized clinical trial (RCT) for Major Depressive Disorder (MDD). MDD self-assessment may vary over time depending on change in the meaning of patients' self-evaluation of depression, i.e. Response Shift (RS). Our aim was to investigate RS and its impact on different depression domains in a clinical trial comparing rTMS versus Venlafaxine. Methods: The occurrence and type of RS was determined using Structural Equation Modeling applied to change over time in 3 domains (Sad Mood, Performance Impairment, Negative Self-Reference) of the short-form Beck Depression Inventory (BDI-13) in a secondary analysis of a RCT on 170 patients with MDD treated by rTMS, venlafaxine or both. Results: RS was evidenced in the venlafaxine group in the Negative Self-Reference and Sad Mood domains. Conclusion: RS effects differed between treatment arms in self-reported depression domains in patients with MDD. Ignoring RS would have led to a slight underestimation of depression improvement, depending on treatment group. Further investigations of RS and advancing new methods are needed to better inform decision making based on Patient-Reported Outcomes. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | hal-04030560; https://hal.science/hal-04030560Test; https://hal.science/hal-04030560/documentTest; https://hal.science/hal-04030560/file/manuscrit%20complet.pdfTest |
| DOI: | 10.1016/j.jpsychires.2023.02.016 |
| الإتاحة: | https://doi.org/10.1016/j.jpsychires.2023.02.016Test https://hal.science/hal-04030560Test https://hal.science/hal-04030560/documentTest https://hal.science/hal-04030560/file/manuscrit%20complet.pdfTest |
| حقوق: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.F24503A2 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.jpsychires.2023.02.016 |
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