دورية أكاديمية
Effect of the use of an endotracheal tube and stylet versus an endotracheal tube alone on first-attempt intubation success: a multicentre, randomised clinical trial in 999 patients
| العنوان: | Effect of the use of an endotracheal tube and stylet versus an endotracheal tube alone on first-attempt intubation success: a multicentre, randomised clinical trial in 999 patients |
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| المؤلفون: | Jaber, Samir, Rollé, Amélie, Godet, Thomas, Terzi, Nicolas, Riu, Béatrice, Asfar, Pierre, Bourenne, Jeremy, Ramin, Séverin, Lemiale, Virginie, Quenot, Jean-Pierre, Guitton, Christophe, Prudhomme, Eloi, Quemeneur, Cyril, Blondonnet, Raiko, Biais, Mathieu, Muller, Laurent, Ouattara, Alexandre, Ferrandiere, Martine, Saint-Léger, Piehr, Rimmelé, Thomas, Pottecher, Julien, Chanques, Gerald, Belafia, Fouad, Chauveton, Claire, Huguet, Helena, Asehnoune, Karim, Futier, Emmanuel, Azoulay, Elie, Molinari, Nicolas, de Jong, Audrey |
| المساهمون: | Physiologie & médecine expérimentale du Cœur et des Muscles U 1046 (PhyMedExp), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier), Centre Hospitalier de Basse-Terre Guadeloupe, Pôle de Médecine Périopératoire CHU Clermont-Ferrand, CHU Gabriel Montpied Clermont-Ferrand, CHU Clermont-Ferrand-CHU Clermont-Ferrand, Centre Hospitalier Universitaire CHU Grenoble (CHUGA), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), CHU d'Angers Département Urgences, Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM), Hôpital de la Timone CHU - APHM (TIMONE), Service d'Anesthésie-Réanimation AP-HP Hôpitaux Saint-Louis Lariboisière, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Lariboisière-Fernand-Widal APHP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Cité (UPCité), Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Lipides - Nutrition - Cancer Dijon - U1231 (LNC), Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement, Centre d'Investigation Clinique 1432 (Dijon) - Epidemiologie Clinique/Essais Cliniques (CIC-EC), Université de Bourgogne (UB)-Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service Réanimation médico-chirurgicale CH Le Mans, Centre Hospitalier Le Mans (CH Le Mans), Service Anesthésie et Réanimation Hôpital Nord - APHM, Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Hôpital Nord CHU - APHM, Centre d'études et de recherche sur les services de santé et la qualité de vie (CEReSS), Aix Marseille Université (AMU), Groupe de Recherche Clinique en Anesthésie Réanimation médecine PEriopératoire (GRC 29 - ARPE), Sorbonne Université (SU), CHU Clermont-Ferrand, Service Anesthésie - Réanimation Bordeaux, CHU Bordeaux, Université de Bordeaux Ségalen Bordeaux 2, Unité de réanimation médicale CHU de Carémeau, Nîmes, Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Magellan Medico-Surgical Center Bordeaux, Adaptation cardiovasculaire à l'ischémie, Université de Bordeaux (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Centre hospitalier Valenciennes, Nord, Hôpital Edouard Herriot CHU - HCL, Hospices Civils de Lyon (HCL), Physiopathologie de l'immunodépression associée aux réponses inflammatoires systémiques / Pathophysiology of Injury-induced Immunosuppression (PI3), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Department of Anesthesiology, Intensive care and Perioperative medicine - Hautepierre Hospital, Strasbourg, Mitochondrie, Stress oxydant et Protection musculaire (MSP), Université de Strasbourg (UNISTRA), Université de Montpellier (UM), Institut Montpelliérain Alexander Grothendieck (IMAG), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Hôtel-Dieu de Nantes |
| المصدر: | ISSN: 0342-4642. |
| بيانات النشر: | HAL CCSD Springer Verlag |
| سنة النشر: | 2021 |
| المجموعة: | HAL Lyon 1 (University Claude Bernard Lyon 1) |
| مصطلحات موضوعية: | Acute respiratory failure, Airway, Complications, Critical care, Intensive care unit, Intubation, Stylet, MESH: Adult, MESH: Critical illness, MESH: Humans, MESH: Intubation, Intratracheal / adverse effects, [SDV]Life Sciences [q-bio] |
| الوصف: | International audience ; Purpose: The effect of the routine use of a stylet during tracheal intubation on first-attempt intubation success is unclear. We hypothesised that the first-attempt intubation success rate would be higher with tracheal tube + stylet than with tracheal tube alone.Methods: In this multicentre randomised controlled trial, conducted in 32 intensive care units, we randomly assigned patients to tracheal tube + stylet or tracheal tube alone (i.e. without stylet). The primary outcome was the proportion of patients with first-attempt intubation success. The secondary outcome was the proportion of patients with complications related to tracheal intubation. Serious adverse events, i.e., traumatic injuries related to tracheal intubation, were evaluated.Results: A total of 999 patients were included in the modified intention-to-treat analysis: 501 (50%) to tracheal tube + stylet and 498 (50%) to tracheal tube alone. First-attempt intubation success occurred in 392 patients (78.2%) in the tracheal tube + stylet group and in 356 (71.5%) in the tracheal tube alone group (absolute risk difference, 6.7; 95%CI 1.4-12.1; relative risk, 1.10; 95%CI 1.02-1.18; P = 0.01). A total of 194 patients (38.7%) in the tracheal tube + stylet group had complications related to tracheal intubation, as compared with 200 patients (40.2%) in the tracheal tube alone group (absolute risk difference, - 1.5; 95%CI - 7.5 to 4.6; relative risk, 0.96; 95%CI 0.83-1.12; P = 0.64). The incidence of serious adverse events was 4.0% and 3.6%, respectively (absolute risk difference, 0.4; 95%CI, - 2.0 to 2.8; relative risk, 1.10; 95%CI 0.59-2.06. P = 0.76).Conclusions: Among critically ill adults undergoing tracheal intubation, using a stylet improves first-attempt intubation success. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/34032882; hal-03236249; https://hal.science/hal-03236249Test; https://hal.science/hal-03236249/documentTest; https://hal.science/hal-03236249/file/2021%20Jaber%20et%20al.,%20Effect%20of%20the%20use.pdfTest; PUBMED: 34032882; PUBMEDCENTRAL: PMC8144872 |
| DOI: | 10.1007/s00134-021-06417-y |
| الإتاحة: | https://doi.org/10.1007/s00134-021-06417-yTest https://hal.science/hal-03236249Test https://hal.science/hal-03236249/documentTest https://hal.science/hal-03236249/file/2021%20Jaber%20et%20al.,%20Effect%20of%20the%20use.pdfTest |
| حقوق: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.15A0A51F |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s00134-021-06417-y |
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