دورية أكاديمية
Decline of semen quality among 10 932 males consulting for couple infertility over a 20-year period in Marseille, France
| العنوان: | Decline of semen quality among 10 932 males consulting for couple infertility over a 20-year period in Marseille, France |
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| المؤلفون: | Geoffroy-Siraudin, Cendrine, Loundou, Anderson Dieudonne, Romain, Fanny, Achard, Vincent, Courbiere, Blandine, Perrard, Marie-Hélène, Durand, Philippe, Guichaoua, Marie-Roberte |
| المساهمون: | Hôpital de la Conception CHU - APHM (LA CONCEPTION), Centre National de la Recherche Scientifique (CNRS), Université de la Méditerranée - Aix-Marseille 2, Institut de Génomique Fonctionnelle de Lyon (IGFL), École normale supérieure de Lyon (ENS de Lyon)-Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS) |
| المصدر: | ISSN: 1008-682X. |
| بيانات النشر: | HAL CCSD Wolters Kluwer – Medknow |
| سنة النشر: | 2012 |
| المجموعة: | HAL Lyon 1 (University Claude Bernard Lyon 1) |
| مصطلحات موضوعية: | male infertility, regional differences, semen quality, sperm parameters, HUMAN EJACULATED SPERMATOZOA, MALE REPRODUCTIVE HEALTH, SPERM DNA-DAMAGE, FERTILE MEN, BIRTH COHORTS, NO EVIDENCE, environment, TESTICULAR DYSGENESIS SYNDROME, PAST 20 YEARS, ENVIRONMENTAL-FACTORS, ANDROGEN-RECEPTOR, [SDV]Life Sciences [q-bio], [INFO]Computer Science [cs] |
| الوصف: | International audience ; Semen from 10 932 male partners of infertile couples was analysed and sperm parameter trends were evaluated at the Reproduction Biology Laboratory of the University Hospital of Marseille (France) between 1988 and 2007. After 3-6 days of abstinence, semen samples were collected. Measurements of seminal fluid volume, pH, sperm concentration, total sperm count, motility and detailed morphology of spermatozoa were performed. Sperm parameters were analysed on the entire population and in men with normal total numeration (>= 40 million per ejaculate). The whole population demonstrated declining trends in sperm concentration (1.5% per year), total sperm count (1.6% per year), total motility (0.4% per year), rapid motility (5.5% per year) and normal morphology (2.2% per year). In the group of selected samples with total normal sperm count, the same trends of sperm quality deterioration with time were observed. Our results clearly indicate that the quality of semen decreased in this population over the study period. Asian Journal of Andrology (2012) 14, 584-590; doi:10.1038/aja.2011.173; published online 23 April 2012 |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | hal-02646080; https://hal.inrae.fr/hal-02646080Test; https://hal.inrae.fr/hal-02646080/documentTest; https://hal.inrae.fr/hal-02646080/file/2012_Geoffroy%20Siraudin_Asian%20Journal%20of%20Andrology_1.pdfTest; PRODINRA: 214647; WOS: 000305998300017 |
| DOI: | 10.1038/aja.2011.173 |
| الإتاحة: | https://doi.org/10.1038/aja.2011.173Test https://hal.inrae.fr/hal-02646080Test https://hal.inrae.fr/hal-02646080/documentTest https://hal.inrae.fr/hal-02646080/file/2012_Geoffroy%20Siraudin_Asian%20Journal%20of%20Andrology_1.pdfTest |
| حقوق: | http://creativecommons.org/licenses/by-nc-saTest/ ; info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.7CF1567F |
| قاعدة البيانات: | BASE |
| DOI: | 10.1038/aja.2011.173 |
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