دورية أكاديمية
Severe atypical pneumonia in critically ill patients: a retrospective multicenter study
| العنوان: | Severe atypical pneumonia in critically ill patients: a retrospective multicenter study |
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| المؤلفون: | Valade, S., Biard, Lucie, Lemiale, V., Argaud, Laurent, Pene, F., Papazian, L., Bruneel, F., Seguin, A., Kouatchet, A., Oziel, J., Rouleau, S., Bele, N., Razazi, K., Lesieur, O., Boissier, F., Megarbane, B., Bige, N., Brule, N., Moreau, A. S., Lautrette, A., Peyrony, O., Perez, P., Mayaux, J., Azoulay, E. |
| المساهمون: | Hopital Saint-Louis AP-HP (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Diderot - Paris 7 (UPD7), Hôpital Edouard Herriot CHU - HCL, Hospices Civils de Lyon (HCL), Unité de Recherche sur les Maladies Infectieuses Tropicales Emergentes (URMITE), Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut des sciences biologiques - CNRS Biologie (INSB-CNRS)-Institut des sciences biologiques - CNRS Biologie (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut des sciences biologiques - CNRS Biologie (INSB-CNRS)-Institut des sciences biologiques - CNRS Biologie (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier de Versailles André Mignot (CHV), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Centre Hospitalier d'Angoulême (CH Angoulême), Centre Hospitalier de la Dracénie Draguignan, Hôpital Européen Georges Pompidou APHP (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes), Hôpital Roger Salengro Lille, CHU Gabriel Montpied Clermont-Ferrand, CHU Clermont-Ferrand, Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy) |
| المصدر: | ISSN: 2110-5820 ; Annals of Intensive Care ; https://hal.science/hal-02003573Test ; Annals of Intensive Care, 2018, 8, pp.81. ⟨10.1186/s13613-018-0429-z⟩. |
| بيانات النشر: | HAL CCSD SpringerOpen |
| سنة النشر: | 2018 |
| المجموعة: | HAL Lyon 1 (University Claude Bernard Lyon 1) |
| مصطلحات موضوعية: | Pneumonia, Chlamydophila pneumoniae, Mycoplasma pneumoniae, ICU, Outcome, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie |
| الوصف: | International audience ; Background: Chlamydophila pneumoniae (CP) and Mycoplasma pneumoniae (MP) patients could require intensive care unit (ICU) admission for acute respiratory failure.Methods: Adults admitted between 2000 and 2015 to 20 French ICUs with proven atypical pneumonia were retrospectively described Patients with MP were compared to Streptococcus pneumoniae (SP) pneumonia patients admitted to ICUs.Results: A total of 104 patients were included, 71 men and 33 women, with a median age of 56[44-67] years. MP was the causative agent for 76(73%) patients and CP for 28(27%) patients. Co-infection was documented for 18 patients (viruses for 8[47%] patients). Median number of involved quadrants on chest X-ray was 2[1-4], with alveolar opacities (n = 61,75%), interstitial opacities (n = 32,40%). Extra-pulmonary manifestations were present in 34 (33%) patients. Mechanical ventilation was required for 75(72%) patients and vasopressors for 41(39%) patients. ICU length of stay was 16.5[9.5-30.5] days, and 11(11%) patients died in the ICU. Compared with SP patients, MP patients had more extensive interstitial pneumonia, fewer pleural effusion, and a lower mortality rate [6(8%) vs. 17(22%), p = 0.013]. According MCA analysis, some characteristics at admission could discriminate MP and SP.MP was more often associated with hemolytic anemia, abdominal manifestations, and extensive chest radiograph abnormalities. SP-P was associated with shock, confusion, focal crackles, and focal consolidation.Conclusion: In this descriptive study of atypical bacterial pneumonia requiring ICU admission, mortality was 11%. The comparison with SP pneumonia identified clinical, laboratory, and radiographic features that may suggest MP or CP pneumonia. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | hal-02003573; https://hal.science/hal-02003573Test; https://hal.science/hal-02003573/documentTest; https://hal.science/hal-02003573/file/s13613-018-0429-z.pdfTest |
| DOI: | 10.1186/s13613-018-0429-z |
| الإتاحة: | https://doi.org/10.1186/s13613-018-0429-zTest https://hal.science/hal-02003573Test https://hal.science/hal-02003573/documentTest https://hal.science/hal-02003573/file/s13613-018-0429-z.pdfTest |
| حقوق: | http://creativecommons.org/licenses/byTest/ ; info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.8CD9CB27 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1186/s13613-018-0429-z |
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