دورية أكاديمية
Characterization of the Unconventional Secretion of the Ebola Matrix Protein VP40
| العنوان: | Characterization of the Unconventional Secretion of the Ebola Matrix Protein VP40 |
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| المؤلفون: | Reynard, Olivier, Mateo, Mathieu |
| المساهمون: | Bases moléculaires de la pathogénicité virale – Molecular Basis of Viral Pathogenicity (BMPV), Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Biologie des Infections Virales Émergentes - Biology of Emerging Viral Infections (UBIVE), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur Paris (IP) |
| المصدر: | ISSN: 1064-3745. |
| بيانات النشر: | HAL CCSD Humana Press/Springer Imprint |
| سنة النشر: | 2016 |
| المجموعة: | HAL Lyon 1 (University Claude Bernard Lyon 1) |
| مصطلحات موضوعية: | Cell Death, Ebola, Ebola virus, Endoplasmic Reticulum, Flow Cytometry, Golgi Apparatus, HEK293 Cells, Humans, L-Lactate Dehydrogenase, Nucleoproteins, Protein Transport, Secretory Pathway, Unconventional secretion, Viral Core Proteins, Virus, VP40, [SDV.IMM]Life Sciences [q-bio]/Immunology, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology |
| الوصف: | International audience ; While most secreted proteins use the classical endoplasmic reticulum (ER)-Golgi secretion pathway to reach the extracellular medium, a few proteins are secreted through unconventional secretary pathways. Viral proteins can be secreted through unconventional secretion pathways. Here, we describe how we have recently demonstrated that the Ebola virus (EBOV) matrix protein VP40 is released from transfected and infected cells in a soluble form through an unconventional secretion pathway. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/27665561; hal-01909000; https://hal.science/hal-01909000Test; PUBMED: 27665561 |
| DOI: | 10.1007/978-1-4939-3804-9_14 |
| الإتاحة: | https://doi.org/10.1007/978-1-4939-3804-9_14Test https://hal.science/hal-01909000Test |
| رقم الانضمام: | edsbas.5CF1C63F |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/978-1-4939-3804-9_14 |
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