دورية أكاديمية
Sodium status and replacement in children and adults living with cystic fibrosis : a narrative review
| العنوان: | Sodium status and replacement in children and adults living with cystic fibrosis : a narrative review |
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| المؤلفون: | Declercq, Dimitri, Van Braeckel, Eva, Marchand, Sophie, Van daele, Sabine, Van Biervliet, Stephanie |
| المصدر: | JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS ; ISSN: 2212-2672 ; ISSN: 2212-2680 |
| سنة النشر: | 2020 |
| المجموعة: | Ghent University Academic Bibliography |
| مصطلحات موضوعية: | Medicine and Health Sciences, Food Science, Nutrition and Dietetics, General Medicine, Cystic fibrosis, Sodium, Salt, Nutritional status, Pseudo-Bartter syndrome, CHLORIDE CONCENTRATION, METABOLIC ALKALOSIS, INFANTS, EXERCISE, SWEAT, IVACAFTOR, NA+ |
| الوصف: | Patients with cystic fibrosis (CF) have a two- to four-fold higher sodium chloride sweat content compared with healthy controls. This high sweat salt loss increases the risk for electrolyte disturbances, associated with subacute or chronic complications. Sodium status therefore needs to be adequately monitored and salt intake adjusted to individual needs. The lack of current evidence to formulate specific recommendations and assess sodium status is reflected in a variability of recommendations in international guidelines. This narrative review presents an overview of the current evidence. Infants with CF in particular are at risk for severe sodium deficiency, potentially leading to metabolic alkalosis due to low intake and high sweat losses. More research on the assessment of sodium status and efficacy of sodium chloride supplements in the population of patients with CF, especially given the changing era of CF transmembrane conductance regulator modulatory treatment, is warranted. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://biblio.ugent.be/publication/8675145Test; http://hdl.handle.net/1854/LU-8675145Test; http://dx.doi.org/10.1016/j.jand.2020.05.011Test; https://biblio.ugent.be/publication/8675145/file/8675146Test |
| DOI: | 10.1016/j.jand.2020.05.011 |
| الإتاحة: | https://doi.org/10.1016/j.jand.2020.05.011Test https://biblio.ugent.be/publication/8675145Test http://hdl.handle.net/1854/LU-8675145Test https://biblio.ugent.be/publication/8675145/file/8675146Test |
| حقوق: | No license (in copyright) ; info:eu-repo/semantics/restrictedAccess |
| رقم الانضمام: | edsbas.25EA8AC4 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.jand.2020.05.011 |
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