دورية أكاديمية
The masquerading presentation of a systemic anaplastic large cell lymphoma, ALK positive : a case report and review of the literature
| العنوان: | The masquerading presentation of a systemic anaplastic large cell lymphoma, ALK positive : a case report and review of the literature |
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| المؤلفون: | Al-Ahmad, Selma, Maertens, Vincent, Libeer, Christophe, Schelfhout, Vera, Vanhoenacker, Filip, Boeckx, Nancy, Vandevenne, Marleen |
| المصدر: | ACTA CLINICA BELGICA ; ISSN: 1784-3286 |
| سنة النشر: | 2017 |
| المجموعة: | Ghent University Academic Bibliography |
| مصطلحات موضوعية: | Medicine and Health Sciences, Anaplastic large cell lymphoma, ALK positive, Leukemic involvement, Respiratory failure, NON-HODGKINS-LYMPHOMA, PEDIATRIC ONCOLOGY, FRENCH SOCIETY, SPECTRUM, CHILDREN, DISEASE |
| الوصف: | We report an unusual case of systemic anaplastic large cell lymphoma (ALCL), ALK positive with leukemic involvement in a 57-year-old woman. The patient presented with a fulminant respiratory infection unresponsive to treatment requiring intensive care and ventilatory support. The CT scan demonstrated mediastinal and bilateral lymphadenopathy. On peripheral smear a few atypical lymphocytes were visualized. Based on the increasing number of atypical lymphocytes in the daily peripheral bloodsmears, the diagnosis ALCL was suggested. Definitive diagnosis was made on a bone marrow biopsy, with lymphocytes being immunoreactive for CD30, EMA, and ALK. Leukemic peripheral blood involvement in ALCL is an uncommon clinicopathologic entity with unfavorable prognosis. The case we present is perhaps unusual in that a complete respons was achieved, highlighting the importance of prompt diagnosis and judicious management. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://biblio.ugent.be/publication/8519128Test; http://hdl.handle.net/1854/LU-8519128Test; http://dx.doi.org/10.1080/17843286.2017.1312057Test; https://biblio.ugent.be/publication/8519128/file/8519129Test |
| DOI: | 10.1080/17843286.2017.1312057 |
| الإتاحة: | https://doi.org/10.1080/17843286.2017.1312057Test https://biblio.ugent.be/publication/8519128Test http://hdl.handle.net/1854/LU-8519128Test https://biblio.ugent.be/publication/8519128/file/8519129Test |
| حقوق: | No license (in copyright) ; info:eu-repo/semantics/restrictedAccess |
| رقم الانضمام: | edsbas.4E036949 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1080/17843286.2017.1312057 |
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