كتاب
Pharmacotherapy of insomnia in older adults
| العنوان: | Pharmacotherapy of insomnia in older adults |
|---|---|
| المؤلفون: | Petrovic, Mirko |
| المساهمون: | Cherubini, Antonio, Mangoni, Arduino, O'Mahony, Denis, Petrovic, Mirko |
| المصدر: | Optimizing pharmacotherapy in older patients : an interdisciplinary approach ; ISSN: 2509-6060 ; ISSN: 2509-6079 ; ISBN: 9783031280603 ; ISBN: 9783031280634 ; ISBN: 9783031280610 |
| بيانات النشر: | Springer Nature |
| سنة النشر: | 2023 |
| المجموعة: | Ghent University Academic Bibliography |
| مصطلحات موضوعية: | Medicine and Health Sciences, insomnia, pharmacotherapy, older adults, benzodiazepines, Z-drugs, antidepressants, melatonin receptor agonists, orexin receptor antagonists |
| الوصف: | Independently from age related changes, sleep problems affect 10-15% of the general population and increase with older age as well. Insomnia is the most prevalent and the most researched sleep disturbance. In this chapter, the pharmacological treatment options have been discussed. Pharmacological treatments are categorised as benzodiazepines (BZDs) and non-benzodiazepine receptor agonists (so called Z-drugs), as the most commonly used drug classes, and alternatives including antidepressants, melatonin receptor agonists and orexin receptor antagonists. BZDs and Z-drugs are effective for short-term treatment of insomnia. Older adults, with a higher risk of side-effects, need tailored pre¬scribing which also includes deprescribing. Different antidepressants, including trazodone, tricyclic antidepressants (doxepin), and serotonergic antidepressant (mirtazapine), have sedating properties and are often used for the treatment of insomnia. However, despite the fact that these alternatives have been shown to be more effective than placebo at bettering short-term sleep outcomes, the size of effect is variable and the overall estimation of benefit-to-risk ratio is low. The potential benefits of pharmacotherapy on sleep quality and daytime function in older adults should always be balanced against the risk of side-effects and physical and psychological dependence with long-term use. |
| نوع الوثيقة: | book part |
| وصف الملف: | application/zip |
| اللغة: | English |
| ردمك: | 978-3-031-28060-3 978-3-031-28063-4 978-3-031-28061-0 3-031-28060-1 3-031-28063-6 3-031-28061-X |
| العلاقة: | https://biblio.ugent.be/publication/01H3V5504WN4D99FKDB3SR0DDWTest; http://hdl.handle.net/1854/LU-01H3V5504WN4D99FKDB3SR0DDWTest; http://doi.org/10.1007/978-3-031-28061-0_27Test; https://biblio.ugent.be/publication/01H3V5504WN4D99FKDB3SR0DDW/file/01H3V5M7KGRPEWNYZKVMMJY2PBTest |
| DOI: | 10.1007/978-3-031-28061-0_27 |
| الإتاحة: | https://doi.org/10.1007/978-3-031-28061-0_27Test https://biblio.ugent.be/publication/01H3V5504WN4D99FKDB3SR0DDWTest http://hdl.handle.net/1854/LU-01H3V5504WN4D99FKDB3SR0DDWTest https://biblio.ugent.be/publication/01H3V5504WN4D99FKDB3SR0DDW/file/01H3V5M7KGRPEWNYZKVMMJY2PBTest |
| حقوق: | No license (in copyright) ; info:eu-repo/semantics/embargoedAccess |
| رقم الانضمام: | edsbas.7D7032BF |
| قاعدة البيانات: | BASE |
| ردمك: | 9783031280603 9783031280634 9783031280610 3031280601 3031280636 303128061X |
|---|---|
| DOI: | 10.1007/978-3-031-28061-0_27 |