دورية أكاديمية
Impaired social functioning in children with narcolepsy
| العنوان: | Impaired social functioning in children with narcolepsy |
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| المؤلفون: | Quaedackers, Laury, van Gilst, Merel M, van Mierlo, Petra, Lammers, Gert-Jan, Dhondt, Karlien, Amesz, Pauline, Peeters, Els, Hendriks, Danielle, Vandenbussche, Nele, Pillen, Sigrid, Overeem, Sebastiaan |
| المصدر: | SLEEP ; ISSN: 1550-9109 |
| بيانات النشر: | Oxford University Press (OUP) |
| سنة النشر: | 2019 |
| المجموعة: | Ghent University Academic Bibliography |
| مصطلحات موضوعية: | Medicine and Health Sciences, narcolepsy, NT1, pediatric, social, behavior, Social Responsiveness Scale, Child Behavior Checklist, QUALITY-OF-LIFE, PSYCHIATRIC COMORBIDITY, AUTISM, HYPOCRETIN/OREXIN, DISORDERS, SPECTRUM, IDENTIFICATION, DIAGNOSIS, NEURONS |
| الوصف: | Study Objectives: To explore impairments in social functioning in children with narcolepsy compared to healthy children. Methods: Parents of 53 pediatric patients with narcolepsy type 1 and 64 matched healthy children completed the Social Responsiveness Scale (SRS) and the Child Behavior Checklist 6-18 (CBCL 6-18). Results: Patients scored significantly higher on the total score of the SRS (median 56, interquartile range [IQR] 23.5) compared to controls (median 44.5, IQR 8.5, U = 797.0, p < 0.001). Patients also scored higher on the sum of the CBCL 6-18 subscales indicative of social functioning (Withdrawn/Depressed, Social Problems, and Thought Problems; median 183, IQR 30.5) compared to controls (median 155, IQR 13, U = 500.0, p < 0.001). A total of 24 patients (45.3%) reported at least mild-to-moderate difficulties in social functioning compared to seven controls (10.9%, chi(2) = 17.165, p < 0.001). Eleven patients (20.8%) and only one control (1.6%) had T scores above 75, which points to severely impaired social functioning (chi(2) = 11.602, p = 0.001). Within the patient group, girls reported mild-to-moderate difficulties in social functioning significantly more often compared to boys on the SRS (77.8% versus 28.6%, chi(2) = 17.560, p < 0.001). Conclusions: Impaired social functioning is common in children with narcolepsy type 1, especially in girls. Questionnaires such as the SRS and the CBCL 6-18 may help in early detection of social problems in pediatric narcolepsy. Recognition of these problems could be valuable in the management of young people with narcolepsy. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://biblio.ugent.be/publication/8613654Test; http://hdl.handle.net/1854/LU-8613654Test; http://dx.doi.org/10.1093/sleep/zsy228Test; https://biblio.ugent.be/publication/8613654/file/8613655Test |
| DOI: | 10.1093/sleep/zsy228 |
| الإتاحة: | https://doi.org/10.1093/sleep/zsy228Test https://biblio.ugent.be/publication/8613654Test http://hdl.handle.net/1854/LU-8613654Test https://biblio.ugent.be/publication/8613654/file/8613655Test |
| حقوق: | No license (in copyright) ; info:eu-repo/semantics/restrictedAccess |
| رقم الانضمام: | edsbas.E49237EA |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/sleep/zsy228 |
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