التفاصيل البيبلوغرافية
| العنوان: |
Rationale for combined therapies in severe-to-critical COVID-19 patients |
| المؤلفون: |
Gonzaga, Aitor, Andreu, Etelvina, Hernández-Blasco, Luis M., Meseguer, Rut, Al-Akioui-Sanz, Karima, Soria-Juan, Bárbara, Sanjuan-Gimenez, Jose Carlos, Ferreras, Cristina, Tejedo, Juan R., Lopez-Lluch, Guillermo, Goterris, Rosa, Maciá, Loreto, Sempere-Ortells, Jose M., Hmadcha, Abdelkrim, Borobia, Alberto, Vicario, Jose L., Bonora, Ana, Aguilar-Gallardo, Cristobal, Poveda, Jose L., Arbona, Cristina, Alenda, Cristina, Tarín, Fabian, Marco, Francisco M., Merino, Esperanza, Jaime, Francisco, Ferreres, José, Figueira, Juan Carlos, Cañada-Illana, Carlos, Querol, Sergio, Guerreiro, Manuel, Eguizabal, Cristina, Martín-Quirós, Alejandro, Robles-Marhuenda, Ángel, Pérez-Martínez, Antonio, Solano, Carlos, Soria, Bernat |
| المصدر: |
Frontiers in Immunology ; volume 14 ; ISSN 1664-3224 |
| بيانات النشر: |
Frontiers Media SA |
| سنة النشر: |
2023 |
| المجموعة: |
Frontiers (Publisher - via CrossRef) |
| مصطلحات موضوعية: |
Immunology, Immunology and Allergy |
| الوصف: |
An unprecedented global social and economic impact as well as a significant number of fatalities have been brought on by the coronavirus disease 2019 (COVID-19), produced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Acute SARS-CoV-2 infection can, in certain situations, cause immunological abnormalities, leading to an anomalous innate and adaptive immune response. While most patients only experience mild symptoms and recover without the need for mechanical ventilation, a substantial percentage of those who are affected develop severe respiratory illness, which can be fatal. The absence of effective therapies when disease progresses to a very severe condition coupled with the incomplete understanding of COVID-19’s pathogenesis triggers the need to develop innovative therapeutic approaches for patients at high risk of mortality. As a result, we investigate the potential contribution of promising combinatorial cell therapy to prevent death in critical patients. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| DOI: |
10.3389/fimmu.2023.1232472 |
| DOI: |
10.3389/fimmu.2023.1232472/full |
| الإتاحة: |
https://doi.org/10.3389/fimmu.2023.1232472Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.35B885E3 |
| قاعدة البيانات: |
BASE |
