دورية أكاديمية
Anti-inflammatory properties of antidiabetic drugs: a “promised land” in the COVID-19 era?
| العنوان: | Anti-inflammatory properties of antidiabetic drugs: a “promised land” in the COVID-19 era? |
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| المؤلفون: | Katsiki, Niki, Ferrannini, Ele |
| المصدر: | reponame:Expeditio Repositorio Institucional UJTL ; instname:Universidad de Bogotá Jorge Tadeo Lozano |
| بيانات النشر: | Journal of Diabetes and Its Complications |
| سنة النشر: | 2020 |
| المجموعة: | Expeditio - Repositorio Institucional Universidad de Bogotá Jorge Tadeo Lozano (UTADEO) |
| مصطلحات موضوعية: | Metformin, Pioglitazone, Dipeptidyl peptidase 4 inhibitors, Glucagon-like peptide-1 receptor agonists, Sodium-glucose co-transporter-2 inhibitors, C-reactive protein, Interleukin 6, Ferritin, Síndrome respiratorio agudo grave, COVID-19, SARS-CoV-2, Coronavirus |
| الوصف: | Inflammation is implicated in the development and severity of the coronavirus disease 2019 (COVID-19), as well as in the pathophysiology of diabetes. Diabetes, especially when uncontrolled, is also recognized as an important risk factor for COVID-19 morbidity and mortality. Furthermore, certain inflammatory markers [i.e. C-reactive protein (CRP), interleukin6 (IL-6) and ferritin] were reported as strong predictors of worse outcomes in COVID-19 positive patients. The same biomarkers have been associated with poor glycemic control. Therefore, achieving euglycemia in patients with diabetes is even more important in the era of the COVID-19 pandemic. Based on the above, it is clinically interesting to elucidate whether antidiabetic drugs may reduce inflammation, thus possibly minimizing the risk for COVID-19 development and severity. The present narrative review discusses the potential anti-inflammatory properties of certain antidiabetic drugs (i.e. metformin, pioglitazone, sitagliptin, linagliptin, vildagliptin, alogliptin, saxagliptin, liraglutide, dulaglutide, exenatide, lixisenatide, semaglutide, empagliflozin, dapagliflozin, canagliflozin), with a focus on CRP, IL-6 and ferritin. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | 39 páginas; image/jepg; image/png |
| اللغة: | English |
| تدمد: | 1056-8727 |
| العلاقة: | https://doi.org/10.1016/j.jdiacomp.2020.107723Test; http://hdl.handle.net/20.500.12010/12859Test |
| DOI: | 10.1016/j.jdiacomp.2020.107723 |
| الإتاحة: | https://doi.org/20.500.12010/12859Test https://doi.org/10.1016/j.jdiacomp.2020.107723Test https://hdl.handle.net/20.500.12010/12859Test |
| حقوق: | info:eu-repo/semantics/embargoedAccess ; Acceso restringido |
| رقم الانضمام: | edsbas.64213C9D |
| قاعدة البيانات: | BASE |
| تدمد: | 10568727 |
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| DOI: | 10.1016/j.jdiacomp.2020.107723 |