دورية أكاديمية
Injectable Self-Healing Glucose-Responsive Hydrogels with pH-Regulated Mechanical Properties
| العنوان: | Injectable Self-Healing Glucose-Responsive Hydrogels with pH-Regulated Mechanical Properties |
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| المؤلفون: | Yesilyurt, Volkan, Webber, Matthew, Appel, Eric, Godwin, Colin, Langer, Robert S, Anderson, Daniel Griffith |
| المساهمون: | Massachusetts Institute of Technology. Institute for Medical Engineering & Science, Harvard University--MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology. Department of Chemical Engineering, Koch Institute for Integrative Cancer Research at MIT, Yesilyurt, Volkan, Webber, Matthew, Appel, Eric, Godwin, Colin, Langer, Robert S, Anderson, Daniel Griffith |
| المصدر: | PMC |
| بيانات النشر: | Wiley Blackwell |
| سنة النشر: | 2015 |
| المجموعة: | DSpace@MIT (Massachusetts Institute of Technology) |
| الوصف: | Dynamically restructuring pH-responsive hydrogels are synthesized, employing dynamic covalent chemistry between phenylboronic acid and cis-diol modified poly(ethylene glycol) macromonomers. These gels display shear-thinning behavior, followed by a rapid structural recovery (self-healing). Size-dependent in vitro controlled and glucose-responsive release of proteins from the hydrogel network, as well as the biocompatibility of the gels, are evaluated both in vitro and in vivo. ; Leona M. and Harry B. Helmsley Charitable Trust (Award 2014PG-T1D002) ; National Institutes of Health (U.S.) (Ruth L. Kirschstein National Research Service Award F32DK101335) ; Wellcome Trust-MIT Postdoctoral Fellowship |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0935-9648 1521-4095 |
| العلاقة: | http://dx.doi.org/10.1002/adma.201502902Test; Advanced Materials; http://hdl.handle.net/1721.1/107195Test; Yesilyurt, Volkan et al. “Injectable Self-Healing Glucose-Responsive Hydrogels with pH-Regulated Mechanical Properties.” Advanced Materials 28.1 (2016): 86–91.; orcid:0000-0001-9944-3562; orcid:0000-0003-0624-3532; orcid:0000-0002-2301-7126; orcid:0000-0003-4255-0492; orcid:0000-0001-5629-4798 |
| الإتاحة: | https://doi.org/10.1002/adma.201502902Test http://hdl.handle.net/1721.1/107195Test |
| حقوق: | Creative Commons Attribution-Noncommercial-Share Alike ; http://creativecommons.org/licenses/by-nc-sa/4.0Test/ |
| رقم الانضمام: | edsbas.4F5780C7 |
| قاعدة البيانات: | BASE |
| تدمد: | 09359648 15214095 |
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