دورية أكاديمية
Thiol disulfide homeostasis in primary dysmenorrhea
| العنوان: | Thiol disulfide homeostasis in primary dysmenorrhea |
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| المؤلفون: | Savrun, Atakan, Savrun, Şeyda Tuba, Dirican, Ebubekir, Gökçen, Emre, Arıcı Yeliz Kaşko, Aygün, Ali, Korkmaz, Vakkas, Neşelioğlu, Salim, Erel, Özcan, Kıran, Tuğba Raika |
| المساهمون: | Mühendislik ve Doğa Bilimleri Fakültesi -- Biyomedikal Mühendisliği Bölümü, Kıran, Tuğba Raika |
| بيانات النشر: | Pharmamed Mado Ltd |
| سنة النشر: | 2022 |
| المجموعة: | DSpace@ISTE (Iskenderun Technical University Institutional Repository) |
| مصطلحات موضوعية: | Oxidative stress, Primary dysmenorrhea, ROC analysis, TDH, Thiol-disulfide, Randomized Controlled Trial, Acupressure, Mefenamic Acid, Emergency Medicine, Clinical & Life Sciences - Fertility, Endometriosis & Hysterectomy - Premenstrual Syndrome, Menstrual disorders, Malondialdehyde, Balance, Albumin, Contraceptive agent, Thiol derivative, Abdominal disease, Biochemical analysis, Body mass, Case control study, Controlled study, Demographics, Dysmenorrhea, Ectopic pregnancy, Emergency ward, Female, Homeostasis, Hospital, Human |
| الوصف: | Oxidative stress is defined as a result of the loss of balance between the production of free radical or reactive oxygen species and the antioxidant system. This study aimed to determine the level of thiol-disulfide homeostasis (TDH) in the serum of women with primary dysmenorrhea. The study group consisted of 42 subjects with primary dysmenorrhea, and the control group consisted of 30 volunteer women with demographic characteristics similar to the study group. Native thiol (SH), total thiol (TSH), disulphide (SS), and SH/SS parameters were measured for TDH of the subjects. The SH (p = 0.038) and SH/TSH (p = 0.046) levels were significantly higher while SS (p = 0.013), SS/SH (p = 0.042) and SS/TSH (p = 0.046) levels were lower in the study group than in the healthy control group. The SS cut-off value was determined as 17.85 in the study group (sensitivity = 61.9%, specificity = 43.3%). Therefore, the probability of dysmenorrhea may increase significantly when SS levels fall below this value. In subjects with dysmenorrhea, there was a decrease in SS levels and an increase in SH levels in order to protect the cells and tissues from the harmful effects of free radicals. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | Signa Vitae; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; Web of Science - Scopus; Web of Science Core Collection - Science Citation Index Expanded; Savrun, A., Savrun, Ş.T., Dirican, E., Gökçen, E., Arıcı, Y.K., Aygün, A., Korkmaz, V., Neşelioğlu, S., Erel, Ö., Kıran, T.R. (2022). Thiol disulfide homeostasis in primary dysmenorrhea. Signa Vitae, 18 (2), pp. 97-103.; http://www.signavitae.com/articles/10.22514/sv.2021.151Test; https://hdl.handle.net/20.500.12508/2219Test |
| DOI: | 10.22514/sv.2021.151 |
| الإتاحة: | https://doi.org/20.500.12508/2219Test https://hdl.handle.net/20.500.12508/2219Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.B5E87645 |
| قاعدة البيانات: | BASE |
| DOI: | 10.22514/sv.2021.151 |
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