دورية أكاديمية
GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer
| العنوان: | GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer |
|---|---|
| المؤلفون: | Han,Na, Yuan,Fang, Xian,Peng, Liu,Nan, Liu,Jianmin, Zhang,Haiyan, Zhang,Huayong, Yao,Kai, Yuan,Gangjun |
| بيانات النشر: | Dove Press |
| سنة النشر: | 2019 |
| المجموعة: | Dove Medical Press |
| مصطلحات موضوعية: | OncoTargets and Therapy |
| الوصف: | Na Han,1,2,* Fang Yuan,2,3,* Peng Xian,2,3,* Nan Liu,2,3 Jianmin Liu,4 Haiyan Zhang,1,2 Huayong Zhang,5 Kai Yao,6 Gangjun Yuan2,3 1Health Examination and Oncology Screening Center, Chongqing University Cancer Hospital, Chongqing 400030, People’s Republic of China; 2Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing 400030, People’s Republic of China; 3Department of Urology, Chongqing University Cancer Hospital, Chongqing 400030, People’s Republic of China; 4Department of Otolaryngology Head and Neck Surgery, People’s Hospital of Deyang, Deyang 618000, People’s Republic of China; 5Department of Thyroid and Breast Surgery, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, People’s Republic of China; 6Department of Urology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Gangjun YuanDepartment of Urology, Chongqing University Cancer Hospital, Chongqing 400030, People’s Republic of ChinaTel +86 23 6507 5629Email freeman17@126.comKai YaoDepartment of Urology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, People’s Republic of ChinaTel +86 20 8734 3840Email yaokai@sysucc.org.cnBackground: Bladder cancer (BC) is one of the most prevalent malignancies of the genitourinary system, yet the underlying mechanism of BC progression still remains unclear. Growth arrest and DNA damage-inducible 45 alpha (GADD45a) is a repressive gene implicated in cell cycle regulation, as well as in human cancers development. However, its role in BC remains to be determined.Methods: First, quantitative real-time polymerase chain reaction (PCR) and Western blot assays were used to detect GADD45a expression in BC tissues and ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text/html |
| اللغة: | English |
| العلاقة: | https://www.dovepress.com/gadd45a-mediated-cell-cycle-inhibition-is-regulated-by-p53-in-bladder--peer-reviewed-fulltext-article-OTTTest |
| الإتاحة: | https://doi.org/10.2147/OTT.S222223Test https://www.dovepress.com/gadd45a-mediated-cell-cycle-inhibition-is-regulated-by-p53-in-bladder--peer-reviewed-fulltext-article-OTTTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.B4EE4C24 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |