دورية أكاديمية
Type 2 diabetes: cost-effectiveness of medication adherence and lifestyle interventions
| العنوان: | Type 2 diabetes: cost-effectiveness of medication adherence and lifestyle interventions |
|---|---|
| المؤلفون: | Nerat,Tomaž, Locatelli,Igor, Kos,Mitja |
| بيانات النشر: | Dove Press |
| سنة النشر: | 2016 |
| المجموعة: | Dove Medical Press |
| مصطلحات موضوعية: | Patient Preference and Adherence |
| الوصف: | Tomaž Nerat, Igor Locatelli, Mitja Kos Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia Introduction: Type 2 diabetes is a major burden for the payer, however, with proper medication adherence, diet and exercise regime, complication occurrence rates, and consequently costs can be altered.Aims: The aim of this study was to conduct a cost-effectiveness analysis on real patient data and evaluate which medication adherence or lifestyle intervention is less cost demanding for the payer.Methods: Medline was searched systematically for published type 2 diabetes interventions regarding medication adherence and lifestyle in order to determine their efficacies, that were then used in the cost-effectiveness analysis. For cost-effectiveness analysis-required disease progression simulation, United Kingdom Prospective Diabetes Study Outcomes model 2.0 and Slovenian type 2 diabetes patient cohort were used. The intervention duration was set to 1, 2, 5, and 10 years. Complications and drug costs in euro (EUR) were based on previously published type 2 diabetes costs from the Health Care payer perspective in Slovenia.Results: Literature search proved the following interventions to be effective in type 2 diabetes patients: medication adherence, the Mediterranean diet, aerobic, resistance, and combined exercise. The long-term simulation resulted in no payer net savings. The model predicted following quality-adjusted life-years (QALY) gained and incremental costs for QALY gained (EUR/QALYg) after 10 years of intervention: high-efficacy medication adherence (0.245 QALY; 9,984 EUR/QALYg), combined exercise (0.119 QALY; 46,411 EUR/QALYg), low-efficacy medication adherence (0.075 QALY; 30,967 EUR/QALYg), aerobic exercise (0.069 QALY; 80,798 EUR/QALYg), the Mediterranean diet (0.057 QALY; 27,246 EUR/QALYg), and resistance exercise (0.050 QALY; 111,847 EUR/QALYg).Conclusion: The results suggest that medication adherence intervention is, regarding cost-effectiveness, superior to diet and exercise interventions from the ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text/html |
| اللغة: | English |
| العلاقة: | https://www.dovepress.com/type-2-diabetes-cost-effectiveness-of-medication-adherence-and-lifesty-peer-reviewed-fulltext-article-PPATest |
| الإتاحة: | https://doi.org/10.2147/PPA.S114602Test https://www.dovepress.com/type-2-diabetes-cost-effectiveness-of-medication-adherence-and-lifesty-peer-reviewed-fulltext-article-PPATest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.B140D0A6 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |