مراجعة

The epidemiology of intransient TB-induced hyperglycaemia in previously undiagnosed diabetes mellitus 2 individuals: a protocol for a systematic review and meta-analysis

التفاصيل البيبلوغرافية
العنوان: The epidemiology of intransient TB-induced hyperglycaemia in previously undiagnosed diabetes mellitus 2 individuals: a protocol for a systematic review and meta-analysis
المؤلفون: Menon, Sonia, Francis, Joel, Zdraveska, Natasha, Dusabimana, Alfred, Bhattacharyya, Samit
المصدر: Review
بيانات النشر: BMC
سنة النشر: 2020
المجموعة: Document Server@UHasselt (Universiteit Hasselt)
مصطلحات موضوعية: Tuberculosis, Diabetes mellitus, Intransient hyperglycaemia, Protocol
الوصف: Background Diabetes mellitus (DM) is burgeoning as a global chronic health condition. Some studies suggest that tuberculosis (TB) can even cause diabetes in those not previously known to be diabetic, which as a corollary can add to the already heavy global DM burden. The World Health Organization (WHO) recommends screening for DM at the start of TB treatment; however, it remains to be elucidated which patients with TB-induced hyperglycaemia are at risk for developing DM and who would benefit from a more regular follow-up. This systematic review will aim to firstly synthesise literature on the irreversibility of TB-induced hyperglycaemia in individuals with previously undiagnosed type 2 diabetes mellitus and secondly to synthesise literature on risk factors for progression from TB-induced hyperglycaemia to overt DM in previously undiagnosed. Methods We will search for relevant studies in electronic databases such as PubMed, EMBASE, PROQUEST, and SCOPUS. Furthermore, references will be hand searched to identify other studies. A flow diagram will be drawn to identify the studies retrieved from each database. We will review all publications that include studies containing data on impaired glucose metabolism upon TB diagnosis, and the quality of all eligible studies will be assessed using the Newcastle-Ottawa Scale. We will further conduct a meta-analysis to pool estimates on the risk of progression of persistent hyperglycaemia to overt DM within this population group, as well as the risk factors for this progression. We will use a random effect model to assess heterogeneity, will carry out sensitivity analysis to explore the influence of a single study on the overall estimate, and will report our findings from our systematic review and meta-analysis according to PRISMA guidelines. Egger's test will be performed to explore the presence of selective reporting bias. If data allow, we will perform a subgroup/meta-regression analysis. Summary effects will be reported using odds ratio, hazard ratio, and relative risk ...
نوع الوثيقة: review
وصف الملف: application/pdf
اللغة: English
تدمد: 2046-4053
العلاقة: Systematic reviews, 8 (1) (Art N° 234); http://hdl.handle.net/1942/31437Test; WOS:000485239300001
DOI: 10.1186/s13643-019-1143-0
الإتاحة: https://doi.org/10.1186/s13643-019-1143-0Test
http://hdl.handle.net/1942/31437Test
حقوق: © The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0Test/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0Test/) applies to the data made available in this article, unless otherwise stated. ; info:eu-repo/semantics/openAccess
رقم الانضمام: edsbas.4CA8B9C0
قاعدة البيانات: BASE
الوصف
تدمد:20464053
DOI:10.1186/s13643-019-1143-0