دورية أكاديمية
Molecular mechanisms of COPII vesicle formation
| العنوان: | Molecular mechanisms of COPII vesicle formation |
|---|---|
| المؤلفون: | Lee, Marcus C.S., Miller, Elizabeth A. |
| المصدر: | Lee , M C S & Miller , E A 2007 , ' Molecular mechanisms of COPII vesicle formation ' , Seminars in Cell and Developmental Biology , vol. 18 , no. 4 , pp. 424-434 . https://doi.org/10.1016/j.semcdb.2007.06.007Test |
| سنة النشر: | 2007 |
| المجموعة: | Discovery - University of Dundee Online Publications |
| مصطلحات موضوعية: | Cargo capture, COPII, Endoplasmic reticulum, Transport vesicle, /dk/atira/pure/subjectarea/asjc/1300/1309, name=Developmental Biology, /dk/atira/pure/subjectarea/asjc/1300/1307, name=Cell Biology |
| الوصف: | The first step in protein secretion from eukaryotic cells is mediated by COPII vesicles, known for the cytoplasmic coat proteins that are the minimal machinery required to generate these small transport carriers. The five COPII coat components coordinate to create a vesicle by locally generating membrane curvature and populating the incipient bud with the appropriate cargo. This review describes the molecular details of how the COPII coat sculpts vesicles from the endoplasmic reticulum and highlights some unresolved questions regarding the regulation of this process in the complex environment of the eukaryotic cell. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://discovery.dundee.ac.uk/en/publications/8927ea04-77b3-40ac-8449-0438143b94acTest |
| DOI: | 10.1016/j.semcdb.2007.06.007 |
| الإتاحة: | https://doi.org/10.1016/j.semcdb.2007.06.007Test https://discovery.dundee.ac.uk/en/publications/8927ea04-77b3-40ac-8449-0438143b94acTest http://www.scopus.com/inward/record.url?scp=34548411897&partnerID=8YFLogxKTest |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.C1E9AE4B |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.semcdb.2007.06.007 |
|---|