المؤلفون: Hancock, Rowena, Bertrand, Helene C., Tsujita, Tadayuki, Naz, Shama, El-Bakry, Ayman, Laoruchupong, Jitnueng, Hayes, John D., Wells, Geoff

المصدر: Hancock , R , Bertrand , H C , Tsujita , T , Naz , S , El-Bakry , A , Laoruchupong , J , Hayes , J D & Wells , G 2012 , ' Peptide inhibitors of the Keap1-Nrf2 protein-protein interaction ' , Free Radical Biology and Medicine , vol. 52 , no. 2 , pp. 444-451 . https://doi.org/10.1016/j.freeradbiomed.2011.10.486Test

مصطلحات موضوعية: Fluorescence polarization, Cancer chemoprevention, Compound screening, Nrf2, Keap1, Free radicals, TRANSCRIPTION FACTOR NRF2, OXIDATIVE STRESS, PROTEASOMAL DEGRADATION, GENE-EXPRESSION, DLG MOTIFS, ACTIVATION, MECHANISM, PATHWAY, CANCER, UBIQUITINATION

العلاقة: https://discovery.dundee.ac.uk/en/publications/77201fa1-1d40-464f-8231-055577924b44Test

الإتاحة: https://doi.org/10.1016/j.freeradbiomed.2011.10.486Test
https://discovery.dundee.ac.uk/en/publications/77201fa1-1d40-464f-8231-055577924b44Test

المؤلفون: Higgins, Larry G., Hayes, John D.

المصدر: Higgins , L G & Hayes , J D 2011 , ' Mechanisms of induction of cytosolic and microsomal glutathione transferase (GST) genes by xenobiotics and pro-inflammatory agents ' , Drug Metabolism Reviews , vol. 43 , no. 2 , pp. 92-137 . https://doi.org/10.3109/03602532.2011.567391Test

مصطلحات موضوعية: ARE (Antioxidant Response Element), tBHQ (tert-butylhydroquinone), CAR (Constitutive Androstane Receptor), Chemoprevention, EpRE (Electrophile Response Element), GPEI (Glutathione transferase P Enhancer I), GRE (Glucocorticoid Response Element), GSH (reduced glutathione), Keap1 (Kelch-like ECH-associated protein 1), PBREM (Phenobarbital-Responsive Enhancer Module), XRE (Xenobiotic Response Element), Nrf2 (NF-E2-related factor 2), AhR (Aryl hydrocarbon Receptor), LEUKOTRIENE C-4 SYNTHASE, ANTIOXIDANT RESPONSE ELEMENT, TRANSCRIPTION FACTOR NRF2, ARYL-HYDROCARBON RECEPTOR, PREGNANE-X-RECEPTOR, RAT-LIVER CYTOSOL, YA-SUBUNIT GENE, PROSTAGLANDIN-E SYNTHASE-1, CONSTITUTIVE ANDROSTANE RECEPTOR, PROTEIN-KINASE-C

العلاقة: https://discovery.dundee.ac.uk/en/publications/11a7d71e-4f75-4b8e-bb7c-e7243a44d9adTest

الإتاحة: https://doi.org/10.3109/03602532.2011.567391Test
https://discovery.dundee.ac.uk/en/publications/11a7d71e-4f75-4b8e-bb7c-e7243a44d9adTest

المؤلفون: Kalra, Sukirti, Zhang, Ying, Knatko, Elena V., Finlayson, Stewart, Yamamoto, Masayuki, Dinkova-Kostova, Albena T.

المصدر: Kalra , S , Zhang , Y , Knatko , E V , Finlayson , S , Yamamoto , M & Dinkova-Kostova , A T 2011 , ' Oral Azathioprine Leads to Higher Incorporation of 6-Thioguanine in DNA of Skin than Liver: The Protective Role of the Keap1/Nrf2/ARE Pathway ' , Cancer Prevention Research , vol. 4 , no. 10 , pp. 1665-1674 . https://doi.org/10.1158/1940-6207.CAPR-11-0137Test

مصطلحات موضوعية: TOPICAL PHOTODYNAMIC THERAPY, TRANSCRIPTION FACTOR NRF2, BLOOD LEUKOCYTE DNA, GLUTATHIONE TRANSFERASES, TRANSPLANT RECIPIENTS, GENE-EXPRESSION, MOUSE-LIVER, UVA LIGHT, CANCER, ENZYMES

العلاقة: https://discovery.dundee.ac.uk/en/publications/c990431b-c823-414e-a4ef-bd284922debeTest

الإتاحة: https://doi.org/10.1158/1940-6207.CAPR-11-0137Test
https://discovery.dundee.ac.uk/en/publications/c990431b-c823-414e-a4ef-bd284922debeTest

المؤلفون: Baird, Liam, Dinkova-Kostova, Albena T.

المصدر: Baird , L & Dinkova-Kostova , A T 2011 , ' The cytoprotective role of the Keap1-Nrf2 pathway ' , Archives of Toxicology , vol. 85 , no. 4 , pp. 241-272 . https://doi.org/10.1007/s00204-011-0674-5Test

مصطلحات موضوعية: Keap1, Nrf2, Cytoprotective enzymes, Phase 2 inducer, TRANSCRIPTION FACTOR NRF2, ANTIOXIDANT-RESPONSE ELEMENT, PROTEIN-KINASE-C, NF-KAPPA-B, GLUTATHIONE-S-TRANSFERASE, URINARY-BLADDER CARCINOGENESIS, OXIDATIVE STRESS-RESPONSE, CANCER-PROTECTIVE ENZYMES, ACTIVITY-GUIDED ISOLATION, UBIQUITIN LIGASE COMPLEX

العلاقة: https://discovery.dundee.ac.uk/en/publications/4c6bc939-840c-4d0c-9c12-17c6cc36492dTest

الإتاحة: https://doi.org/10.1007/s00204-011-0674-5Test
https://discovery.dundee.ac.uk/en/publications/4c6bc939-840c-4d0c-9c12-17c6cc36492dTest

المؤلفون: McMahon, Michael, Lamont, Douglas J., Beattie, Kenneth A., Hayes, John D.

المصدر: McMahon , M , Lamont , D J , Beattie , K A & Hayes , J D 2010 , ' Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals ' , Proceedings of the National Academy of Sciences of the United States of America , vol. 107 , no. 44 , pp. 18838-18843 . https://doi.org/10.1073/pnas.1007387107Test

مصطلحات موضوعية: TRANSCRIPTION FACTOR NRF2, OXIDATIVE STRESS, HEME OXYGENASE-1, PROTEASOMAL DEGRADATION, PHASE-2 ENZYMES, CELLULAR STRESS, INDUCTION, PROTEIN, ACTIVATION, CELLS

العلاقة: https://discovery.dundee.ac.uk/en/publications/f804f4aa-0697-4b38-89bf-ee1d1ed82fbcTest

الإتاحة: https://doi.org/10.1073/pnas.1007387107Test
https://discovery.dundee.ac.uk/en/publications/f804f4aa-0697-4b38-89bf-ee1d1ed82fbcTest
http://www.scopus.com/inward/record.url?scp=78650509515&partnerID=8YFLogxKTest

المؤلفون: Lewis, Kaitlyn N., Mele, James, Hayes, John D., Buffenstein, Rochelle

المصدر: Lewis , K N , Mele , J , Hayes , J D & Buffenstein , R 2010 , ' Nrf2, a Guardian of Healthspan and Gatekeeper of Species Longevity ' , Integrative and Comparative Biology , vol. 50 , no. 5 , pp. 829-843 . https://doi.org/10.1093/icb/icq034Test

مصطلحات موضوعية: TRANSCRIPTION FACTOR NRF2, NAKED MOLE-RAT, ANTIOXIDANT-RESPONSE ELEMENT, LONGEST-LIVING RODENT, GLUTAMATE-CYSTEINE LIGASE, FREE-RADICAL THEORY, OXIDATIVE STRESS, LIFE-SPAN, CAENORHABDITIS-ELEGANS, GENE-EXPRESSION

العلاقة: https://discovery.dundee.ac.uk/en/publications/a836b6b7-1d1a-4659-9350-8fe171f3d2f4Test

الإتاحة: https://doi.org/10.1093/icb/icq034Test
https://discovery.dundee.ac.uk/en/publications/a836b6b7-1d1a-4659-9350-8fe171f3d2f4Test

المؤلفون: Calabrese, Vittorio, Cornelius, Carolin, Dinkova-Kostova, Albena T., Calabrese, Edward J., Mattson, Mark P.

المصدر: Calabrese , V , Cornelius , C , Dinkova-Kostova , A T , Calabrese , E J & Mattson , M P 2010 , ' Cellular Stress Responses, The Hormesis Paradigm, and Vitagenes: Novel Targets for Therapeutic Intervention in Neurodegenerative Disorders ' , Antioxidants & Redox Signaling , vol. 13 , no. 11 , pp. 1763-1811 . https://doi.org/10.1089/ars.2009.3074Test

مصطلحات موضوعية: NF-KAPPA-B, TRANSCRIPTION FACTOR NRF2, SHAPED DOSE-RESPONSES, AMYLOID-BETA-PEPTIDE, HEAT-SHOCK PROTEINS, MANGANESE SUPEROXIDE-DISMUTASE, AMYOTROPHIC-LATERAL-SCLEROSIS, CHOLINERGIC DRUG-COMBINATIONS, ENDOPLASMIC-RETICULUM STRESS, CANCER-PROTECTIVE ENZYMES

العلاقة: https://discovery.dundee.ac.uk/en/publications/5125d014-a317-486d-9393-4399d1d17ca3Test

الإتاحة: https://doi.org/10.1089/ars.2009.3074Test
https://discovery.dundee.ac.uk/en/publications/5125d014-a317-486d-9393-4399d1d17ca3Test

المؤلفون: Chowdhry, Sudhir, Nazmy, Maiiada H., Meakin, Paul J., Dinkova-Kostova, Albena T., Walsh, Shaun V., Tsujita, Tadayuki, Dillon, John F., Ashford, Michael L. J., Hayes, John D.

المصدر: Chowdhry , S , Nazmy , M H , Meakin , P J , Dinkova-Kostova , A T , Walsh , S V , Tsujita , T , Dillon , J F , Ashford , M L J & Hayes , J D 2010 , ' Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis ' , Free Radical Biology and Medicine , vol. 48 , no. 2 , pp. 357-371 . https://doi.org/10.1016/j.freeradbiomed.2009.11.007Test

مصطلحات موضوعية: Nonalcoholic steatohepatitis, Methionine- and choline-deficient diet, Nrf2, NF-kappa B, Glutathione, Free radicals, CHOLINE-DEFICIENT DIET, TRANSCRIPTION FACTOR NRF2, FATTY LIVER-DISEASE, GLUTAMATE-CYSTEINE LIGASE, OXIDATIVE STRESS, HEPATIC STEATOSIS, QUANTITATIVE-DETERMINATION, INDUCIBLE EXPRESSION, LIPID-PEROXIDATION, INSULIN-RESISTANCE

العلاقة: https://discovery.dundee.ac.uk/en/publications/4ea4dc90-d8f1-4b83-9c3d-484407bca44fTest

الإتاحة: https://doi.org/10.1016/j.freeradbiomed.2009.11.007Test
https://discovery.dundee.ac.uk/en/publications/4ea4dc90-d8f1-4b83-9c3d-484407bca44fTest

المؤلفون: Hayes, John D., McMahon, Michael, Chowdhry, Sudhir, Dinkova-Kostova, Albena T.

المصدر: Hayes , J D , McMahon , M , Chowdhry , S & Dinkova-Kostova , A T 2010 , ' Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway ' , Antioxidants & Redox Signaling , vol. 13 , no. 11 , pp. 1713-1748 . https://doi.org/10.1089/ars.2010.3221Test

مصطلحات موضوعية: GLUTATHIONE-S-TRANSFERASE, ANTIOXIDANT RESPONSE ELEMENT, TRANSCRIPTION FACTOR NRF2, HEME OXYGENASE-1 GENE, GAMMA-GLUTAMYLCYSTEINE SYNTHETASE, URINARY-BLADDER CARCINOGENESIS, YA-SUBUNIT GENE, HUMAN DIHYDRODIOL DEHYDROGENASE, MICHAEL REACTION ACCEPTORS, GLUTAMATE-CYSTEINE LIGASE

العلاقة: https://discovery.dundee.ac.uk/en/publications/8361afc8-92b0-45b4-81c9-e7162ac709ebTest

الإتاحة: https://doi.org/10.1089/ars.2010.3221Test
https://discovery.dundee.ac.uk/en/publications/8361afc8-92b0-45b4-81c9-e7162ac709ebTest

المؤلفون: Kitteringham, Neil R., Abdullah, Azman, Walsh, Joanne, Randle, Laura, Jenkins, Rosalind E., Sison, Rowena, Goldring, Christopher E. P., Powell, Helen, Sanderson, Christopher, Williams, Samantha, Higgins, Larry, Yamamoto, Masayuki, Hayes, John, Park, B. Kevin

المصدر: Kitteringham , N R , Abdullah , A , Walsh , J , Randle , L , Jenkins , R E , Sison , R , Goldring , C E P , Powell , H , Sanderson , C , Williams , S , Higgins , L , Yamamoto , M , Hayes , J & Park , B K 2010 , ' Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver ' , Journal of Proteomics , vol. 73 , no. 8 , pp. 1612-1631 . https://doi.org/10.1016/j.jprot.2010.03.018Test

مصطلحات موضوعية: Nrf2, Transgenic, Liver, Protein expression, iTRAQ, Lipid metabolism, GAMMA-GLUTAMYLCYSTEINE SYNTHETASE, ANTIOXIDANT RESPONSIVE ELEMENT, TRANSCRIPTION FACTOR NRF2, CONTROLLING INDUCIBLE EXPRESSION, SUBUNIT GENE-EXPRESSION, HEME OXYGENASE-1 GENE, HIGH-FAT DIET, OXIDATIVE STRESS, MOUSE-LIVER, OLIGONUCLEOTIDE MICROARRAY

العلاقة: https://discovery.dundee.ac.uk/en/publications/7573ef7c-32a9-44ff-89f5-ad078a952663Test

الإتاحة: https://doi.org/10.1016/j.jprot.2010.03.018Test
https://discovery.dundee.ac.uk/en/publications/7573ef7c-32a9-44ff-89f5-ad078a952663Test