المؤلفون: Humpton, Timothy J., Nomura, Koji, Weber, Julia, Magnussen, Helge M., Hock, Andreas K., Nixon, Colin, Dhayade, Sandeep, Stevenson, David, Huang, Danny T., Strathdee, Douglas J. C., Blyth, Karen, Vousden, Karen H.

المصدر: Humpton , T J , Nomura , K , Weber , J , Magnussen , H M , Hock , A K , Nixon , C , Dhayade , S , Stevenson , D , Huang , D T , Strathdee , D J C , Blyth , K & Vousden , K H 2021 , ' Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice ' , Genes & Development , vol. 35 , no. 1-2 , pp. 117-132 . https://doi.org/10.1101/gad.341875.120Test

مصطلحات موضوعية: MDM2, p53, E3 activity, RING mutant

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/cf09e4db-a06d-451c-b2dc-9ad3b9beec65Test

الإتاحة: https://doi.org/10.1101/gad.341875.120Test
https://discovery.dundee.ac.uk/en/publications/cf09e4db-a06d-451c-b2dc-9ad3b9beec65Test
https://discovery.dundee.ac.uk/ws/files/73209500/Genes_Dev._2021_Humpton_117_32.pdfTest

المؤلفون: Magnussen, Helge M., Ahmed, Syed F., Sibbet, Gary J., Hristova, Ventzislava A., Nomura, Koji, Hock, Andreas K., Archibald, Lewis J., Jamieson, Andrew G., Fushman, David, Vousden, Karen H., Weissman, Allan M., Huang, Danny T.

المصدر: Magnussen , H M , Ahmed , S F , Sibbet , G J , Hristova , V A , Nomura , K , Hock , A K , Archibald , L J , Jamieson , A G , Fushman , D , Vousden , K H , Weissman , A M & Huang , D T 2020 , ' Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain ' , Nature Communications , vol. 11 , 2094 . https://doi.org/10.1038/s41467-020-15783-yTest

مصطلحات موضوعية: DNA damage response, Proteolysis, Structural biology, Ubiquitin ligases, X-ray crystallography, /dk/atira/pure/subjectarea/asjc/1600/1600, name=General Chemistry, /dk/atira/pure/subjectarea/asjc/1300/1300, name=General Biochemistry,Genetics and Molecular Biology, /dk/atira/pure/subjectarea/asjc/3100/3100, name=General Physics and Astronomy

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/a582251c-89fd-43e4-899c-ec14379efbe7Test

الإتاحة: https://doi.org/10.1038/s41467-020-15783-yTest
https://discovery.dundee.ac.uk/en/publications/a582251c-89fd-43e4-899c-ec14379efbe7Test
https://discovery.dundee.ac.uk/ws/files/55225916/s41467_020_15783_y.pdfTest
http://www.scopus.com/inward/record.url?scp=85084003202&partnerID=8YFLogxKTest