دورية أكاديمية
Stereotactic Radiosurgery for Benign Cavernous Sinus Meningiomas: A Multicentre Study and Review of the Literature
| العنوان: | Stereotactic Radiosurgery for Benign Cavernous Sinus Meningiomas: A Multicentre Study and Review of the Literature |
|---|---|
| المؤلفون: | Santacroce, Antonio, Tuleasca, Constantin, Liščák, Roman, Motti, Enrico, Lindquist, Christer, Radatz, Matthias, Gatterbauer, Brigitte, Lippitz, Bodo E., Martínez Álvarez, Roberto, Martínez Moreno, Nuria, Kamp, Marcel A., Sandvei Skeie, Bente, Schipmann, Stephanie, Longhi, Michele, Unger, Frank, Sabin, Ian, Mindermann, Thomas, Bundschuh, Otto, Horstmann, Gerhard A., van Eck, A.T.C. J., Walier, Maja, Berres, Manfred, Nakamura, Makoto, Steiger, Hans Jakob, Hänggi, Daniel, Fortmann, Thomas, Alsofy, Samer Zawy, Régis, Jean, Ewelt, Christian |
| المساهمون: | W. McDermott, Michael |
| سنة النشر: | 2022 |
| المجموعة: | Digital Library Thüringen |
| مصطلحات موضوعية: | article, ScholarlyArticle, ddc:610, meningioma, cavernous sinus, stereotactic radiosurgery, Gamma Knife, multicentre study |
| الوصف: | Simple Summary Meningiomas are the most common tumours of the central nervous system (CNS). Despite their benign histology, proximity to critical neurovascular structures may lead to significant morbidity with tumour growth. This is the case for cavernous sinus meningiomas (CSMs), as their growth may surround critical neuro-vascular structures and cause significant morbidity. Radical microsurgical resection carries a high risk of additional neurological deficits, as well as the risk of death. Current management of these tumours, where treatment is indicated, has moved away from radical surgery towards radiotherapy/radiosurgery. This is particularly the case for patients who have residual or recurring tumours after previous surgery. There are many reports that describe the effectiveness of using stereotactic radiosurgery (SRS) for CSMs; however, large cohort analyses are lacking. This multicentre analysis reports the outcome data of over 1000 patients with CSMs who were treated with SRS. SRS shows a high local tumour control rate with few complications. These results agree with previous reports in the literature. SRS is a valuable primary or adjuvant treatment option for CSMs. Abstract Cavernous sinus meningiomas (CSMs) remain a surgical challenge due to the intimate involvement of their contained nerves and blood vessels. Stereotactic radiosurgery (SRS) is a safe and effective minimally invasive alternative for the treatment of small- to medium-sized CSMs. Objective: To assess the medium- to long-term outcomes of SRS for CSMs with respect to tumour growth, prevention of further neurological deterioration and improvement of existing neurological deficits. This multicentric study included data from 15 European institutions. We performed a retrospective observational analysis of 1222 consecutive patients harbouring 1272 benign CSMs. All were treated with Gamma Knife stereotactic radiosurgery (SRS). Clinical and imaging data were retrieved from each centre and entered into a common database. All tumours with imaging ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | 19 Seiten |
| اللغة: | English |
| العلاقة: | Cancers -- Cancers (Basel) -- 2072-6694 -- 2527080-1 -- http://uri.gbv.de/document/gvk:ppn:614095670Test; https://doi.org/10.3390/cancers14164047Test; https://nbn-resolving.org/urn:nbn:de:gbv:27-dbt-20221115-112327-005Test; https://www.db-thueringen.de/receive/dbt_mods_00053867Test; https://www.db-thueringen.de/servlets/MCRFileNodeServlet/dbt_derivate_00057644/cancers-14-04047-v3.pdfTest |
| DOI: | 10.3390/cancers14164047 |
| الإتاحة: | https://doi.org/10.3390/cancers14164047Test https://nbn-resolving.org/urn:nbn:de:gbv:27-dbt-20221115-112327-005Test https://www.db-thueringen.de/receive/dbt_mods_00053867Test https://www.db-thueringen.de/servlets/MCRFileNodeServlet/dbt_derivate_00057644/cancers-14-04047-v3.pdfTest |
| حقوق: | Open Access related to alliance or national license ; public ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.A87AD724 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/cancers14164047 |
|---|