المؤلفون: Herman, Anne, Baeck, Marie

المساهمون: UCL - (SLuc) Service de dermatologie, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - (SLuc) Centre de l'allergie

المصدر: Contact dermatitis, Vol. 85, no. 1, p. 105-106 (2021)

مصطلحات موضوعية: Acrylates, Allergens, Belgium, Camphanes, Dermatitis, Allergic Contact, Occupational, Female, Humans, Male, Medical Staff, Hospital, Patch Tests, allergic contact dermatitis, glucose sensor, insulin pump, isobornyl acrylate, medical device, sensitization

الوصف: Allergic contact dermatitis (ACD) to isobornyl acrylate (IBOA) hasbeen largely reported. Consequently, it was recognized as the“Con-tact Allergen of the Year 2020â€by the American Contact DermatitisSociety. The prevalence of IBOA sensitization is estimated to be 0.7%to 3.8% in patients with adverse skin reactions to medical devices(MDs) used in diabetes.1,2However, to our knowledge, the prevalenceof sensitization to IBOA in the general patch-tested population hasnot yet been established. [.]

العلاقة: boreal:260955; http://hdl.handle.net/2078.1/260955Test; info:pmid/33527358; urn:ISSN:0105-1873; urn:EISSN:1600-0536

الإتاحة: https://doi.org/10.1111/cod.13797Test
http://hdl.handle.net/2078.1/260955Test

المؤلفون: Herman, Anne, Baeck, Marie, de Montjoye, Laurence, Bruze, Magnus, Giertz, Emil, Goossens, An, Mowitz, Martin

المساهمون: UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - (SLuc) Service de dermatologie

المصدر: Contact dermatitis, Vol. 81, no.6, p. 432-437 (2019)

مصطلحات موضوعية: Acrylates, Allergic contact dermatitis, Delayed hypersensitivity, Glucose sensor, Insulin pump, Isobornyl acrylate, Medical device

الوصف: BACKGROUND: The FreeStyle Libre glucose sensor has caused many cases of allergic contact dermatitis, and isobornyl acrylate (IBOA) in this sensor has been identified as one of the culprit allergens. OBJECTIVES: To report on the presence of IBOA in devices produced by Medtronic, namely, the Enlite sensor and the insulin infusion set Paradigm MiniMed Quick-set. PATIENTS AND METHODS: Five patients reacting to the glucose sensor Enlite and/or the insulin infusion set Paradigm MiniMed Quick-set observed in three clinics (two Belgian and one Swedish) were patch tested with the baseline and other series, as well as with IBOA; four of them also with pieces of adhesive patches from the devices, and two with a thin layer chromatogram of Enlite glucose sensor extracts. Gas chromatography-mass spectrometry (GC-MS) analyses were performed. RESULTS: Four patients reacted to IBOA and one to colophonium, a known allergen in Enlite, and three to the adhesive part of the sensor or the insulin infusion set. IBOA was identified in the sensor by GC-MS, and its presence was indicated in the infusion set. CONCLUSIONS: IBOA is a contact allergen in Enlite glucose sensor, and likely also in the infusion set. Therefore, these devices are not suitable alternatives for patients sensitized to the FreeStyle Libre sensor.

العلاقة: boreal:225644; http://hdl.handle.net/2078.1/225644Test; info:pmid/31385313; urn:ISSN: 0105-1873; urn:EISSN:1600-0536

الإتاحة: https://doi.org/10.1111/cod.13374Test
http://hdl.handle.net/2078.1/225644Test