دورية أكاديمية
Closed-Loop Neuromodulation for Parkinson’s Disease: Current State and Future Directions
| العنوان: | Closed-Loop Neuromodulation for Parkinson’s Disease: Current State and Future Directions |
|---|---|
| المؤلفون: | Kim, Samhwan, Kang, Seongtak, Kim, Jinmo, Lee, Doyoung, Kim, Sanghee, Lee, Junghyup, Jang, Kyung-In, Oh, Yong-Seok, Rah, Jong-Cheol, Huh, Man Seung, Paek, Sun Ha, Choi, Ji-Woong |
| بيانات النشر: | Institute of Electrical and Electronics Engineers Inc. |
| سنة النشر: | 2020 |
| المجموعة: | DGIST Scholar (Daegu Gyeongbuk Institute of Science & Technology) |
| مصطلحات موضوعية: | Closed-loop system, Deep brain stimulation, Neuromodulation, Parkinson&apos, s disease, DEEP-BRAIN-STIMULATION, DOPA-INDUCED DYSKINESIA, SUBTHALAMIC NUCLEUS STIMULATION, 5-HT1A RECEPTOR STIMULATION, HIGH-FREQUENCY STIMULATION, STIMULUS ARTIFACT REMOVAL, CARBIDOPA INTESTINAL GEL, NEURONAL-ACTIVITY, SUBSTANTIA-NIGRA, BASAL GANGLIA |
| الوصف: | Deep brain stimulation (DBS) refers to a neurosurgical process in which electrical stimulation is delivered via electrodes implanted within deep brain regions. DBS has become the most established clinical therapy for patients with movement disorders, although recent studies have investigated its application in a broad range of neurological and psychiatric disorders as well. Moreover, DBS has proven effective in controlling symptoms in patients with Parkinson’s disease (PD). While early DBS systems were capable of stimulation only, technological advancements have allowed for the direct assessment of dysfunctional brain activity and subsequent stimulation of the pathological circuitry. DBS can also be combined with neurochemical stimulation to address decreased concentrations of dopamine in the brain. Given that both electrical and neurochemical treatments for PD aim to rectify abnormalities in neural activity, the general term “neuromodulation” is considered more accurate and comprehensive. Recent improvements in signal detection and information processing techniques have provided further insight into PD mechanisms, which may aid in the development of personalized biomarkers and in the prediction of symptoms. In this comprehensive review, we discuss various aspects of neuromodulation in patients with PD, including basic theories, stimulation paradigms, and current challenges in the field. IEEE ; FALSE ; scopus |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2332-7804 |
| العلاقة: | Engineering; Telecommunications; Engineering, Electrical & Electronic; Telecommunications; http://hdl.handle.net/20.500.11750/12553Test; 000728132600004; 2-s2.0-85096376794; IEEE Transactions on Molecular, Biological, and Multi-Scale Communications, v.7, no.4, pp.209 - 223 |
| DOI: | 10.1109/TMBMC.2020.3036756 |
| الإتاحة: | https://doi.org/20.500.11750/12553Test https://doi.org/10.1109/TMBMC.2020.3036756Test https://hdl.handle.net/20.500.11750/12553Test |
| رقم الانضمام: | edsbas.8D449AE9 |
| قاعدة البيانات: | BASE |
| تدمد: | 23327804 |
|---|---|
| DOI: | 10.1109/TMBMC.2020.3036756 |