دورية أكاديمية
Profiling cellular diversity in sponges informs animal cell type and nervous system evolution
| العنوان: | Profiling cellular diversity in sponges informs animal cell type and nervous system evolution |
|---|---|
| المؤلفون: | Musser, Jacob, Schippers, Klaske J., Wolf, Florian, Liang, Cong, Hernández-Plaza, Ana, Cantalapiedra, Carlos P., Achim, Kaia, Schieber, Nicole L., Pan, Leslie, Ruperti, Fabian, Francis, Warren R., Vargas, Sergio, Nickel, Michael, Kling, Svenja, Renkert, Maike, Polikarpov, Maxim, Bourenkov, Gleb, Feuda, Roberto, Gaspar, Imre, Burkhardt, Pawel, Wang, Bo, Bork, Peer, Beck, Martin, Mizzon, Giulia, Schneider, Thomas R., Kreshuk, Anna, Wörheide, Gert, Huerta-Cepas, Jaime, Schwab, Yannick, Moroz, Leonid L., Arendt, Detlev, Kohn, Andrea B., Pape, Constantin, Ronchi, Paolo, Papadopoulos, Nikolaos, Tarashansky, Alexander J., Hammel, Jörg U. |
| المصدر: | Science / Science now 374(6568), 717 - 723 (2021). doi:10.1126/science.abj2949 |
| بيانات النشر: | Assoc. |
| سنة النشر: | 2021 |
| المجموعة: | DESY Publication Database (PUBDB) |
| مصطلحات موضوعية: | info:eu-repo/classification/ddc/320 |
| جغرافية الموضوع: | DE |
| الوصف: | The evolutionary origin of metazoan cell types such as neurons and muscles is not known. Using whole-body single-cell RNA sequencing in a sponge, an animal without nervous system and musculature, we identified 18 distinct cell types. These include nitric oxide–sensitive contractile pinacocytes, amoeboid phagocytes, and secretory neuroid cells that reside in close contact with digestive choanocytes that express scaffolding and receptor proteins. Visualizing neuroid cells by correlative x-ray and electron microscopy revealed secretory vesicles and cellular projections enwrapping choanocyte microvilli and cilia. Our data show a communication system that is organized around sponge digestive chambers, using conserved modules that became incorporated into the pre- and postsynapse in the nervous systems of other animals. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/issn/1095-9203; info:eu-repo/semantics/altIdentifier/pmid/pmid:34735222; info:eu-repo/semantics/altIdentifier/issn/0036-8075; info:eu-repo/semantics/altIdentifier/issn/1947-8062; info:eu-repo/semantics/altIdentifier/wos/WOS:000714952000030; https://bib-pubdb1.desy.de/record/471482Test; https://bib-pubdb1.desy.de/search?p=id:%22PUBDB-2021-04435%22Test |
| الإتاحة: | https://doi.org/10.1126/science.abj2949Test https://bib-pubdb1.desy.de/record/471482Test https://bib-pubdb1.desy.de/search?p=id:%22PUBDB-2021-04435%22Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.812B8964 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |