التفاصيل البيبلوغرافية
العنوان: |
Evaluation of Cardiac Electrophysiological Balance in Patients with Subclinical Hypothyroidism |
المؤلفون: |
ŞAYLIK, Faysal, ÇINAR, Tufan, SELÇUK, Murat, AKBULUT, Tayyar |
المصدر: |
Volume: 25, Issue: 1 77-84 ; 2149-2972 ; 2149-2980 ; Koşuyolu Heart Journal |
بيانات النشر: |
Kartal Koşuyolu Yüksek İhtisas EAH |
سنة النشر: |
2022 |
المجموعة: |
DergiPark Akademik (E-Journals) |
مصطلحات موضوعية: |
Hypothyroidism,cardiac electrophysiology,cardiac arrhythmia |
الوصف: |
Introduction: Subclinical hypothyroidism (SH) is defined by slightly elevated thyroid-stimulating hormone (TSH) levels with normal free triiodothyronine (fT3) and thyroxine (fT4) levels. SH is related to cardiovascular events, including malignant arrhythmias. Cardiac electrophysiological balance (iCEB) and its corrected form with heart rate (iCEBc) are useful electrocardiographic (ECG) parameters for the prediction of malign arrhythmias. In this study, we aimed to evaluate iCEB and iCEBc in SH patients. Patients and Methods: A total of 164 patients (n= 82 patients with SH and n= 82 controls) were enrolled in this study. iCEB was calculated by dividing QT by QRS, and iCEBc was calculated by dividing corrected QT (QTc) by QRS. The groups were compared based on ECG parameters. Correlation and multiple linear regression analyses were used to assess the association of ECG parameters with TSH levels. Results: There were no differences between the groups regarding clinical and laboratory findings. Tp-e, QT, QTc, Tp-e/QT, Tp-e/QTc, iCEB, and iCEBc were significantly prolonged in SH patients compared to controls. In correlation analyses, all of the abovementioned ECG parameters were significantly correlated with serum TSH levels. Multiple linear regression analysis indicated that Tp-e, iCEB, and iCEBc were independently associated with serum TSH levels in SH patients. Conclusion: To our knowledge, this was the first study to demonstrate that iCEB and iCEBc were both prolonged in SH patients compared to controls, and both of them were independently correlated with TSH levels in such patients. |
نوع الوثيقة: |
article in journal/newspaper |
وصف الملف: |
application/pdf |
اللغة: |
English |
العلاقة: |
https://dergipark.org.tr/tr/download/article-file/2385822Test; https://dergipark.org.tr/tr/pub/khj/issue/69468/1106301Test |
الإتاحة: |
https://dergipark.org.tr/tr/pub/khj/issue/69468/1106301Test |
رقم الانضمام: |
edsbas.902CE298 |
قاعدة البيانات: |
BASE |