دورية أكاديمية
Prostate-Specific Antigen Screening and 15-Year Prostate Cancer Mortality: A Secondary Analysis of the CAP Randomized Clinical Trial. ...
العنوان: | Prostate-Specific Antigen Screening and 15-Year Prostate Cancer Mortality: A Secondary Analysis of the CAP Randomized Clinical Trial. ... |
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المؤلفون: | Martin, Richard M, Turner, Emma L, Young, Grace J, Metcalfe, Chris, Walsh, Eleanor I, Lane, J Athene, Sterne, Jonathan AC, Noble, Sian, Holding, Peter, Ben-Shlomo, Yoav, Williams, Naomi J, Pashayan, Nora, Bui, Mai Ngoc, Albertsen, Peter C, Seibert, Tyler M, Zietman, Anthony L, Oxley, Jon, Adolfsson, Jan, Mason, Malcolm D, Davey Smith, George, Neal, David E, Hamdy, Freddie C, Donovan, Jenny L, CAP Trial Group |
بيانات النشر: | American Medical Association (AMA) |
سنة النشر: | 2024 |
المجموعة: | DataCite Metadata Store (German National Library of Science and Technology) |
مصطلحات موضوعية: | Aged, Humans, Male, Middle Aged, Early Detection of Cancer, England, Follow-Up Studies, Mass Screening, Neoplasm Grading, Prostate-Specific Antigen, Prostatic Neoplasms, Wales, Ultrasonography, Image-Guided Biopsy |
الوصف: | IMPORTANCE: The Cluster Randomized Trial of PSA Testing for Prostate Cancer (CAP) reported no effect of prostate-specific antigen (PSA) screening on prostate cancer mortality at a median 10-year follow-up (primary outcome), but the long-term effects of PSA screening on prostate cancer mortality remain unclear. OBJECTIVE: To evaluate the effect of a single invitation for PSA screening on prostate cancer-specific mortality at a median 15-year follow-up compared with no invitation for screening. DESIGN, SETTING, AND PARTICIPANTS: This secondary analysis of the CAP randomized clinical trial included men aged 50 to 69 years identified at 573 primary care practices in England and Wales. Primary care practices were randomized between September 25, 2001, and August 24, 2007, and men were enrolled between January 8, 2002, and January 20, 2009. Follow-up was completed on March 31, 2021. INTERVENTION: Men received a single invitation for a PSA screening test with subsequent diagnostic tests if the PSA level was 3.0 ... |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
DOI: | 10.17863/cam.107668 |
الإتاحة: | https://doi.org/10.17863/cam.107668Test https://www.repository.cam.ac.uk/handle/1810/366944Test |
حقوق: | open.access ; Creative Commons Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0/legalcodeTest ; cc-by-4.0 ; http://purl.org/coar/access_right/c_abf2Test |
رقم الانضمام: | edsbas.399CFC5F |
قاعدة البيانات: | BASE |
DOI: | 10.17863/cam.107668 |
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