دورية أكاديمية
Positive and neutral updating reconsolidate aversive episodic memories via different routes
| العنوان: | Positive and neutral updating reconsolidate aversive episodic memories via different routes |
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| المؤلفون: | Wang, Jingyi, Chen, Boxuan, Sha, Manqi, Gu, Yiran, Wu, Haitao, Forcato, Cecilia, Qin, Shaozheng |
| بيانات النشر: | Academic Press Inc Elsevier Science |
| المجموعة: | CONICET Digital (Consejo Nacional de Investigaciones Científicas y Técnicas) |
| مصطلحات موضوعية: | Episodic memory, Memory updating, Reconsolidation, False memory, https://purl.org/becyt/ford/1.7Test, https://purl.org/becyt/ford/1Test |
| الوصف: | Aversive memories are long-lasting and prone to burden our emotional wellbeing and mental health. Yet, how to remedy the maladaptive effects of aversive memories remains elusive. Using memory reactivation and emotional updating manipulations, we investigated how positive and neutral emotion may update aversive memories for reconsolidation in humans. We found that positive updating after reactivation was equivalent to neutral updating in impairing true memories of a previous aversive event after a 12-hour wakeful delay, but induced more false memory. Moreover, additional 12-hour delay with overnight sleep did not further enlarge true memory differences, but attenuated the effect of reactivation and updating on false memory. Interestingly, the neutral rather than the positive updating reduced the emotional arousal of the aversive memory 24 h later. Our findings could serve as a reference for real-world therapeutic applications regarding how positive and neutral updating may reshape aversive memories, especially when taking wake- and sleep-filled reconsolidation into account. ; Fil: Wang, Jingyi. Beijing Normal University; China ; Fil: Chen, Boxuan. Beijing Normal University; China ; Fil: Sha, Manqi. Beijing Normal University; China ; Fil: Gu, Yiran. East China Normal University; China ; Fil: Wu, Haitao. Beijing Institute of Basic Medical Sciences; China. Chinese Institute for Brain Research; China ; Fil: Forcato, Cecilia. Instituto Tecnológico de Buenos Aires. Departamento de Investigación y Doctorado; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina ; Fil: Qin, Shaozheng. Beijing Normal University; China. Chinese Institute for Brain Research; China |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2692-8205 |
| العلاقة: | info:eu-repo/semantics/altIdentifier/url/https://www.biorxiv.org/content/10.1101/2021.01.04.424701v1Test; info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1074742721001222Test; http://hdl.handle.net/11336/164170Test; Wang, Jingyi; Chen, Boxuan; Sha, Manqi; Gu, Yiran; Wu, Haitao; et al.; Positive and neutral updating reconsolidate aversive episodic memories via different routes; Academic Press Inc Elsevier Science; Neurobiology of Learning and Memory; 184; 107500; 1-2021; 1-41; CONICET Digital; CONICET |
| الإتاحة: | https://doi.org/10.1016/j.nlm.2021.107500Test http://hdl.handle.net/11336/164170Test |
| حقوق: | info:eu-repo/semantics/openAccess ; https://creativecommons.org/licenses/by-nc-nd/2.5/arTest/ |
| رقم الانضمام: | edsbas.43351292 |
| قاعدة البيانات: | BASE |
| تدمد: | 26928205 |
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