التفاصيل البيبلوغرافية
| العنوان: |
International Journal of Surgical Pathology 11(2):101-107, 2003 Progressive Transformation of Germinal Centers: A Clinicopathological Study of 42 Japanese Patients |
| المؤلفون: |
Masaru Kojima, T Shigeo Nakamura, T Tadashi Motoori, Hideaki Itoh, Kazuhiko Shimizu, Tt Nobuo Yamane, Shiro Sugihara, Noriyuki Sakata, Nobuhide Masawa |
| المساهمون: |
The Pennsylvania State University CiteSeerX Archives |
| المصدر: |
http://ijs.sagepub.com/content/11/2/101.full.pdfTest. |
| المجموعة: |
CiteSeerX |
| مصطلحات موضوعية: |
Cancer Center Hospital, Ohta, tDepartment of Pathology |
| الوصف: |
To clarify the clinicopathological features of progressive transformation of germinal center (PTGC) unrelated to nodular lymphocyte predominant Hodgkin's lymphoma in Japanese patients, we reviewed 42 cases and compared the results with those of the United States and Germany. Our results were similar to theirs, with male pre-dominance (M/F ratio, 3:1) and the presentation of a solitary asymptomatic enlarged lymph node in the head and neck area as the common features. However, in Japan, PTGC occurs more frequently in elderly patients. In this study, 12 (29%) of the pa-tients with PTGC were aged 60 years or more. Thirteen patients (31%) with lym-phadenopathy in the neck and head area had developed localized chronic inflamma-tion (chronic sialoadenitis=4, chronic tonsillitis=3, infectious epidermal cyst=2) or an autoimmune disorder (hyperthyroidism=2 and bronchial asthma=2). None of the pa-tients developed a malignant lymphoma during the follow-up period of 5 to 238 months (median 27 months). Histologically, in a single longitudinal section of the lymph node, the PTGC occupied up to 5 % of the total follicles in 22 patients, 5-10% in 10, 10-20 % in 7, and more than 20 % in 3. In 5 (12%) patients, an association with |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1029.8663Test; http://ijs.sagepub.com/content/11/2/101.full.pdfTest |
| الإتاحة: |
http://ijs.sagepub.com/content/11/2/101.full.pdfTest |
| حقوق: |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: |
edsbas.F290604F |
| قاعدة البيانات: |
BASE |
