التفاصيل البيبلوغرافية
| العنوان: |
JCB: ARTICLE Critical requirement for cell cycle inhibitors in sustaining nonproliferative states |
| المؤلفون: |
Deborah Pajalunga, Alessia Mazzola, Anna Maria Salzano, Maria Grazia Biferi, Gabriele De Luca, Marco Crescenzi |
| المساهمون: |
The Pennsylvania State University CiteSeerX Archives |
| المصدر: |
ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/a0/6c/J_Cell_Biol_2007_Mar_12_176(6)_807-818.tar.gz |
| المجموعة: |
CiteSeerX |
| الوصف: |
In adult vertebrates, most cells are not in the cell cycle at any one time. Physiological nonproliferation states encompass reversible quiescence and permanent postmitotic conditions such as terminal differentiation and replicative senescence. Although these states appear to be attained and maintained quite differently, they might share a core proliferation-restricting mechanism. Unexpectedly, we found that all sorts of nonproliferating cells can be mitotically reactivated by the sole suppression of histotypespecific cyclin-dependent kinase (cdk) inhibitors (CKIs) in the absence of exogenous mitogens. RNA interference– mediated suppression of appropriate CKIs effi ciently |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/zip |
| اللغة: |
English |
| العلاقة: |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.283.9751Test |
| حقوق: |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: |
edsbas.2A2D4E8E |
| قاعدة البيانات: |
BASE |
