التفاصيل البيبلوغرافية
| العنوان: |
0888-8809/02/$15.00/0 Molecular Endocrinology 16(6):1407–1416 Printed in U.S.A. Copyright © 2002 by The Endocrine Society AVP Induces Myogenesis through the Transcriptional Activation of the Myocyte Enhancer Factor 2 |
| المؤلفون: |
Bianca Maria Scicchitano, Lucia Spath, Antonio Musarò, Mario Molinaro, Sergio Adamo, Clara Nervi |
| المساهمون: |
The Pennsylvania State University CiteSeerX Archives |
| المصدر: |
http://mend.endojournals.org/content/16/6/1407.full.pdfTest. |
| المجموعة: |
CiteSeerX |
| مصطلحات موضوعية: |
acetyltransferase, DTT, dithiothreitol, FGF, fibroblast growth factor, �gal, �-galactosidase, HAT, histone acetyltransferases, HDAC, histone deacetylase, IGFR, IGF receptor, MEF2, myocyte enhancer factor 2. The neurohypophyseal nonapeptide Arg 8 vasopressin |
| الوصف: |
(AVP) promotes differentiation of cultured L6 and L5 myogenic cell lines and mouse primary satellite cells. Here, we investigated the molecular mechanism involved in the induction of the myogenic program by AVP. In L6 cells, AVP treatment rapidly induces Myf-5, myogenin, and myocyte enhancer factor 2 (MEF2) mRNAs, without affecting the expression of known myogenic growth factors such as IGF-I, IGF-II, or their receptors. In the presence of cycloheximide, AVP up-regulates the expression of MEF2, but not of myogenin, indicating that the synthesis of a protein intermediate is not necessary for MEF2 induction. Notably, AVP treatment activates a calcium/calmodulin kinase signaling pathway that |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.319.8109Test; http://mend.endojournals.org/content/16/6/1407.full.pdfTest |
| الإتاحة: |
http://mend.endojournals.org/content/16/6/1407.full.pdfTest |
| حقوق: |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: |
edsbas.1D194F05 |
| قاعدة البيانات: |
BASE |
