التفاصيل البيبلوغرافية
| العنوان: |
Effect of higher frequency components and duration of vibration on bone tissue alterations in the rat-tail model ; Ind Health |
| المساهمون: |
PEELUKHANA, Srikara V., GOENKA, Shilpi, KIM, Brian, KIM, Jay, BHATTACHARYA, Amit, STRINGER, Keith F., BANERJEE, Rupak K. |
| المصدر: |
Ind Health. 2015; 53(3):245-259. |
| المجموعة: |
CDC Stacks (Centers for Disease Control and Prevention) |
| مصطلحات موضوعية: |
Original Article, Hand-arm vibration syndrome, Resonance frequency, Osteocyte, Biochemical alterations, Nitrotyrosine |
| الوصف: |
To formulate more accurate guidelines for musculoskeletal disorders (MSD) linked to Hand-Arm Vibration Syndrome (HAVS), delineation of the response of bone tissue under different frequencies and duration of vibration needs elucidation. Rat-tails were vibrated at 125 Hz (9 rats) and 250 Hz (9 rats), at 49 m/s(2), for 1D (6 rats), 5D (6 rats) and 20D (6 rats); D=days (4 h/d). Rats in the control group (6 rats for the vibration groups; 2 each for 1D, 5D, and 20D) were left in their cages, without being subjected to any vibration. Structural and biochemical damages were quantified using empty lacunae count and nitrotyrosine signal-intensity, respectively. One-way repeated-measure mixed-model ANOVA at p<0.05 level of significance was used for analysis. In the cortical bone, structural damage quantified through empty lacunae count was significant (p<0.05) at 250 Hz (10.82 ± 0.66) in comparison to the control group (7.41 ± 0.76). The biochemical damage was significant (p<0.05) at both the 125 Hz and 250 Hz vibration frequencies. The structural damage was significant (p<0.05) at 5D for cortical bone while the trabecular bone showed significant (p<0.05) damage at 20D time point. Further, the biochemical damage increased with increase in the duration of vibration with a significant (p<0.05) damage observed at 20D time point and a near significant change (p=0.08) observed at 5D time point. Structural and biochemical changes in bone tissue are dependent upon higher vibration frequencies of 125 Hz, 250 Hz and the duration of vibration (5D, 20D). ; T42/OH008432-06/OH/NIOSH CDC HHS/United States ; 25843564 ; PMC4466877 |
| نوع الوثيقة: |
other/unknown material |
| اللغة: |
unknown |
| العلاقة: |
http://stacks.cdc.gov/view/cdc/32991Test/ |
| الإتاحة: |
http://stacks.cdc.gov/view/cdc/32991Test/ |
| رقم الانضمام: |
edsbas.ADD5E87D |
| قاعدة البيانات: |
BASE |
