دورية أكاديمية
Do Patient-Reported Upper-Body Symptoms Predict Breast Cancer-Related Lymphoedema: Results from a Population-Based, Longitudinal Breast Cancer Cohort Study
| العنوان: | Do Patient-Reported Upper-Body Symptoms Predict Breast Cancer-Related Lymphoedema: Results from a Population-Based, Longitudinal Breast Cancer Cohort Study |
|---|---|
| المؤلفون: | Hayes, S.C, Dunn, M, Plinsinga, M.L, Reul-Hirche, H, Ren, Y, Laakso, E.-L, Troester, M.A |
| المصدر: | Cancers, 14(23) |
| بيانات النشر: | MDPI |
| سنة النشر: | 2022 |
| المجموعة: | Carolina Digital Repository (UNC - University of North Carolina) |
| مصطلحات موضوعية: | symptoms, lymphoedema, upper-body function, cohort study, breast cancer |
| الوصف: | The objectives of this work were to (i) describe upper-body symptoms post-breast cancer; (ii) explore the relationship between symptoms and upper-body function, breast cancer-related lymphoedema (BCRL), physical activity levels, and quality of life; and (iii) determine whether the presence of upper-body symptoms predicts BCRL. Nine symptoms, upper-body function, lymphoedema, physical activity, and quality of life were assessed in women with invasive breast cancer at baseline (2- to 9-months post-diagnosis; n = 2442), and at 2- and 7-years post-diagnosis. Mann–Whitney tests, unpaired t-tests, and chi-squared analyses were used to assess cross-sectional relationships, while regression analyses were used to assess the predictive relationships between symptoms at baseline, and BCRL at 2- and 7-years post-diagnosis. Symptoms are common post-breast cancer and persist at 2- and 7-years post-diagnosis. Approximately two in three women, and one in three women, reported >2 symptoms of at least mild severity, and of at least moderate severity, respectively. The presence of symptoms is associated with poorer upper-body function, and lower physical activity levels and quality of life. One or more symptoms of at least moderate severity increases the odds of developing BCRL by 2- and 7-years post-diagnosis (p < 0.05). Consequently, improved monitoring and management of symptoms following breast cancer have the potential to improve health outcomes. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://doi.org/10.17615/psp2-t864Test; https://cdr.lib.unc.edu/downloads/s7526q69c?file=thumbnailTest; https://cdr.lib.unc.edu/downloads/s7526q69cTest |
| DOI: | 10.17615/psp2-t864 |
| الإتاحة: | https://doi.org/10.17615/psp2-t864Test https://cdr.lib.unc.edu/downloads/s7526q69c?file=thumbnailTest https://cdr.lib.unc.edu/downloads/s7526q69cTest |
| رقم الانضمام: | edsbas.AB72E4E2 |
| قاعدة البيانات: | BASE |
| DOI: | 10.17615/psp2-t864 |
|---|