دورية أكاديمية
Pharmacoepidemiology and 'in silico' drug evaluation: is there common ground?
| العنوان: | Pharmacoepidemiology and 'in silico' drug evaluation: is there common ground? |
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| المؤلفون: | Stürmer, T., Rothman, K.J., Avorn, J. |
| المصدر: | Journal of Clinical Epidemiology, 61(3) |
| سنة النشر: | 2008 |
| المجموعة: | Carolina Digital Repository (UNC - University of North Carolina) |
| مصطلحات موضوعية: | simulation, postmarketing surveillance, pharmacoepidemiology, human, hip fracture, risk factor, article, drug bioavailability, outcome assessment, drug screening, priority journal, benzodiazepine derivative, artifact, risk reduction |
| الوصف: | Shortcomings of randomized trials have long been recognized by medical researchers (1,2). These shortcomings include a reduced range of risk factors for the outcome among patients enrolled in pre-approval trials. The reduced range enhances the validity of the trials, but the patient populations are highly selected compared with the broad range of risk factors represented among patients who are eventually treated with the drug. This restriction may reduce the generalizability of the findings from those studied to those with different baseline risks. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://doi.org/10.17615/kngg-wa44Test; https://cdr.lib.unc.edu/downloads/r207v0404?file=thumbnailTest; https://cdr.lib.unc.edu/downloads/r207v0404Test |
| DOI: | 10.17615/kngg-wa44 |
| الإتاحة: | https://doi.org/10.17615/kngg-wa44Test https://cdr.lib.unc.edu/downloads/r207v0404?file=thumbnailTest https://cdr.lib.unc.edu/downloads/r207v0404Test |
| رقم الانضمام: | edsbas.395AECF2 |
| قاعدة البيانات: | BASE |
| DOI: | 10.17615/kngg-wa44 |
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