دورية أكاديمية
The heterogeneity of LDH isoenzyme patterns of human uterine sarcomas and cultured sarcoma cell lines.
| العنوان: | The heterogeneity of LDH isoenzyme patterns of human uterine sarcomas and cultured sarcoma cell lines. |
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| المؤلفون: | Nelson, Karen G., Siegfried, Jill M., Siegal, Gene P., Becker, Robert, Walton, Leslie A., Kaufman, David G. |
| المصدر: | The American Journal of Pathology, 116(1) |
| سنة النشر: | 1984 |
| المجموعة: | Carolina Digital Repository (UNC - University of North Carolina) |
| مصطلحات موضوعية: | Sarcoma, Lactato deshidrogenasa, Lignée cellulaire, Isozyme, Enzymatic activity, Activité enzymatique, Tumor, Appareil génital femelle pathologie, Human, Isozima, Homme, Utérus, Linea celular, Female genital diseases, Tumeur, Enzyme, Cell line, Heterogeneity, Hétérogénéité, Uterus, Sarcome, Lactate dehydrogenase, Utero |
| الوصف: | Both the tissue lactate dehydrogenase (LDH) isoenzyme pattern and total LDH activity were investigated in a series of human uterine sarcomas and cell lines derived from these tumors. Abnormal LDH isoenzyme patterns characterized by shifts toward the muscle isoenzyme forms (LDH4 and 5) were found in some, but not all, of the sarcomas. The tumors containing rhabdomyosarcomatous elements usually had normal or only slightly altered LDH isoenzyme patterns. The LDH isoenzyme patterns expressed by cultured cell lines established from the uterine sarcomas, in general, resembled those found in the primary tumors. These results suggest that the normal or near normal LDH isoenzyme distributions found in uterine sarcomas with rhabdomyosarcomatous differentiation may be a potential characteristic which may be used for distinguishing these tumors from other uterine sarcomas. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://doi.org/10.17615/za1f-st03Test; https://cdr.lib.unc.edu/downloads/kw52jh20h?file=thumbnailTest; https://cdr.lib.unc.edu/downloads/kw52jh20hTest |
| DOI: | 10.17615/za1f-st03 |
| الإتاحة: | https://doi.org/10.17615/za1f-st03Test https://cdr.lib.unc.edu/downloads/kw52jh20h?file=thumbnailTest https://cdr.lib.unc.edu/downloads/kw52jh20hTest |
| حقوق: | http://rightsstatements.org/vocab/InC/1.0Test/ |
| رقم الانضمام: | edsbas.5A1B89B0 |
| قاعدة البيانات: | BASE |
| DOI: | 10.17615/za1f-st03 |
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