دورية أكاديمية
Gene regulatory networks for development
| العنوان: | Gene regulatory networks for development |
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| المؤلفون: | Levine, Michael, Davidson, Eric H. |
| المصدر: | Proceedings of the National Academy of Sciences of the United States of America, 102(14), 4936-4942, (2005-04-05) |
| بيانات النشر: | National Academy of Sciences |
| سنة النشر: | 2005 |
| المجموعة: | Caltech Authors (California Institute of Technology) |
| مصطلحات موضوعية: | sea-urchin embryo, animal-vegetal axis, CNS midline cells, drosophila embryo, EGF receptor, ventral ectoderm, beta-catenin, spitz class, specification, activation |
| الوصف: | The genomic program for development operates primarily by the regulated expression of genes encoding transcription factors and components of cell signaling pathways. This program is executed by cis-regulatory DNAs (e.g., enhancers and silencers) that control gene expression. The regulatory inputs and functional outputs of developmental control genes constitute network-like architectures. In this PNAS Special Feature are assembled papers on developmental gene regulatory networks governing the formation of various tissues and organs in nematodes, flies, sea urchins, frogs, and mammals. Here, we survey salient points of these networks, by using as reference those governing specification of the endomesoderm in sea urchin embryos and dorsal-ventral patterning in the Drosophila embryo. ; Copyright © 2005 by the National Academy of Sciences. Contributed by Eric H. Davidson and Michael Levine, February 1, 2005. We thank Dmitri Papatsenko for creating Fig. 2 and Angela Stathopoulos and Rob Zinzen for access to unpublished results. This work was supported by National Institutes of Health Grant HD37105. ; Published - LEVpnas05.pdf |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| العلاقة: | https://doi.org/10.1073/pnas.0408031102Test; oai:authors.library.caltech.edu:ed0kj-r3n29; https://www.ncbi.nlm.nih.gov/pmc/PMC555974Test; eprintid:1022; resolverid:CaltechAUTHORS:LEVpnas05 |
| DOI: | 10.1073/pnas.0408031102 |
| الإتاحة: | https://doi.org/10.1073/pnas.0408031102Test https://www.ncbi.nlm.nih.gov/pmc/PMC555974Test |
| حقوق: | info:eu-repo/semantics/openAccess ; Other |
| رقم الانضمام: | edsbas.96466F21 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1073/pnas.0408031102 |
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