دورية أكاديمية
Impact of varicocele repair on semen parameters in infertile men: A systematic review and meta-analysis
العنوان: | Impact of varicocele repair on semen parameters in infertile men: A systematic review and meta-analysis |
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المؤلفون: | Agarwal, Ashok, Cannarella, Rossella, Saleh, Ramadan, Boitrelle, Florence, Gül, Murat, Toprak, Tuncay, Salvio, Gianmaria, Arafa, Mohamed, Russo, Giorgio Ivan, Harraz, Ahmed M., Singh, Rajender, Garrido, Nicolas, Abdel-Meguid Hamoda, Taha Abo-Almagd, Rambhatla, Amarnath, Kavoussi, Parviz, Kuroda, Shinnosuke, Çalik, Gökhan, Saini, Pallavi, Ceyhan, Erman, Dimitriadis, Fotios, Henkel, Ralf, Crafa, Andrea, Palani, Ayad, Duran, Mesut Berkan, Maziotis, Evangelos, Saïs, Émine, Bendayan, Marion, Darbandi, Mahsa, Le, Tan V., Güneş, Sezgin, Tsioulou, Petroula, Sengupta, Pallav, Hazır, Berk, Çeker, Gökhan, Darbandi, Sara, Durairajanayagam, Damayanthi, Aghamajidi, Azin, Alkhalidi, Noora, Sogutdelen, Emrullah, Leisegang, Kristian, Alarbid, Abdullah, Ho, Christopher C. K., Malhotra, Vineet, Finocchi, Federica, Crisóstomo, Luís, Kosgi, Raghavender, Elbardisi, Haitham, Zini, Armand, Birowo, Ponco, Colpi, Giovanni, Park, Hyun Jun, Şerefoğlu, Ege Can, Nguyen, Quang, Ko, Edmund, Rosette, Jean de la, Pinggera, Germar Michael, Nguyen, Ho Vinh Phuoc, Kandil, Hussein, Shah, Rupin |
المساهمون: | Tıp Fakültesi, orcid:0000-0003-0585-1026, orcid:0000-0003-4599-8487, orcid:0000-0003-0503-3533, orcid:0000-0002-5322-0141, orcid:0000-0002-6657-6227, orcid:0000-0003-1348-5273, orcid:0000-0001-9290-5699, orcid:0000-0003-0107-8857, orcid:0000-0003-4687-7353, orcid:0000-0002-8902-517X, orcid:0000-0002-4592-6566, orcid:0000-0001-8271-5218, orcid:0000-0002-8070-4088, orcid:0000-0002-1383-6670, orcid:0000-0001-7390-5837, orcid:0000-0001-8890-0297, orcid:0000-0002-9976-9666, orcid:0000-0003-0072-5573, orcid:0000-0001-8223-6399, orcid:0000-0003-1198-9144, orcid:0000-0003-1128-2982, orcid:0000-0002-8311-9095, orcid:0000-0001-7806-9903, orcid:0000-0002-8597-2081, orcid:0000-0002-6717-166X, orcid:0000-0002-4937-8974, orcid:0000-0003-1633-7735, orcid:0000-0002-2243-9319, orcid:0000-0003-1766-7453, orcid:0000-0002-3103-6482, orcid:0000-0002-3535-8227, orcid:0000-0002-1928-5048, orcid:0000-0002-8907-8781, orcid:0000-0002-7891-9450, orcid:0000-0002-1868-6712, orcid:0000-0001-9049-0215, orcid:0000-0001-5904-5260, orcid:0000-0003-1106-6606, orcid:0000-0002-1454-5672, orcid:0000-0002-3003-8048, orcid:0000-0003-4822-9587, orcid:0000-0002-8757-6867, orcid:0000-0001-6760-0885, orcid:0000-0003-1551-5990, orcid:0000-0002-9563-6364, orcid:0000-0002-2178-0857, orcid:0000-0003-3902-7924, orcid:0000-0002-2194-5578, orcid:0000-0003-2934-6753, orcid:0000-0003-1431-1777, orcid:0000-0003-0566-9574, orcid:0000-0002-2530-7012, orcid:0000-0002-1670-8885, orcid:0000-0002-7465-3616, orcid:0000-0002-6308-1763, orcid:0000-0001-6463-2494, orcid:0000-0002-4348-6034, orcid:0000-0002-5549-3274, orcid:0000-0002-7868-5949 |
بيانات النشر: | Asian Society of Penile Surgery |
سنة النشر: | 2022 |
المجموعة: | Biruni University Institutional Repository (DSpace@Biruni) |
مصطلحات موضوعية: | Male Infertility, Semen, Varicocele |
الوصف: | Purpose: Despite the significant role of varicocele in the pathogenesis of male infertility, the impact of varicocele repair (VR) on conventional semen parameters remains controversial. Only a few systematic reviews and meta-analyses (SRMAs) have evaluated the impact of VR on sperm concentration, total motility, and progressive motility, mostly using a before-after analytic approach. No SRMA to date has evaluated the change in conventional semen parameters after VR compared to untreated controls. This study aimed to evaluate the effect of VR on conventional semen parameters in infertile patients with clinical varicocele compared to untreated controls. Materials and Methods: A literature search was performed using Scopus, PubMed, Embase, and Cochrane databases following the Population Intervention Comparison Outcome (PICOS) model (Population: infertile patients with clinical varicocele; Intervention: VR [any technique]; Comparison: infertile patients with clinical varicocele that were untreated; Outcome: sperm concentration, sperm total count, progressive sperm motility, total sperm motility, sperm morphology, and semen volume; Study type: randomized controlled trials and observational studies). Results: A total of 1,632 abstracts were initially assessed for eligibility. Sixteen studies were finally included with a total of 2,420 infertile men with clinical varicocele (1,424 patients treated with VR vs. 996 untreated controls). The analysis showed significantly improved post-operative semen parameters in patients compared to controls with regards to sperm concentration (standardized mean difference [SMD] 1.739; 95% CI 1.129 to 2.349; p<0.001; I2 =97.6%), total sperm count (SMD 1.894; 95% CI 0.566 to 3.222; p<0.05; I2 =97.8%), progressive sperm motility (SMD 3.301; 95% CI 2.164 to 4.437; p<0.01; I 2 =98.5%), total sperm motility (SMD 0.887; 95% CI 0.036 to 1.738; p=0.04; I2 =97.3%) and normal sperm morphology (SMD 1.673; 95% CI 0.876 to 2.470; p<0.05; I2 =98.5%). All the outcomes showed a high ... |
نوع الوثيقة: | article in journal/newspaper |
وصف الملف: | application/pdf |
اللغة: | English |
تدمد: | 2287-4208 2287-4690 |
العلاقة: | https://doi.org/10.5534/wjmh.220142Test; The World Journal of Men's Health; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://hdl.handle.net/20.500.12445/2800Test; 22 |
DOI: | 10.5534/wjmh.220142 |
الإتاحة: | https://doi.org/20.500.12445/2800Test https://doi.org/10.5534/wjmh.220142Test https://hdl.handle.net/20.500.12445/2800Test |
حقوق: | info:eu-repo/semantics/openAccess |
رقم الانضمام: | edsbas.4103BF04 |
قاعدة البيانات: | BASE |
تدمد: | 22874208 22874690 |
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DOI: | 10.5534/wjmh.220142 |