التفاصيل البيبلوغرافية
| العنوان: |
Female-to-male sex reversal in orange-spotted grouper (Epinephelus coioides) caused by overexpressing of Amh in vivo† |
| المؤلفون: |
Yulong Han, Cheng Peng, Le Wang, Jiani Guo, Mingwei Lu, Jiaxin Chen, Yun Liu, Shuisheng Li, Mi Zhao, Yong Zhang, Haoran Lin |
| المساهمون: |
Yulong Han, Cheng Peng, Le Wang, Jiani Guo, Mingwei Lu, Jiaxin Chen, Yun Liu, Shuisheng Li, Mi Zhao, Yong Zhang, Haoran Lin |
| المصدر: |
https://doi.org/10.1093/biolre/ioy157Test. |
| بيانات النشر: |
Society for the Study of Reproduction |
| سنة النشر: |
2018 |
| المجموعة: |
BioOne Online Journals |
| جغرافية الموضوع: |
world |
| الوصف: |
A variety of mechanisms are involved in sex determination in vertebrates. The orange-spotted grouper (Epinephelus coioides), a teleost fish, functions first as females and later as a male and is an ideal model to investigate the regulation of sexual fate. Here, we report female-to-male sex reversal in juvenile orange-spotted groupers caused by overexpressing anti-Müllerian hormone (Amh). Tissue distribution analyses showed that amh and amhrII primarily expressed in the gonad, and expression level in the testis wasmuch higher than that in the ovary. In gonads, the expression of amh was located in the Sertoli cells around spermatogonia of the testis and in the zona pellucida of the mature ovary, and the expression of amhrII was located in the Sertoli cells of the testis and in the oocytes of the ovary. Decrease in female-related genes and serum 17β-estradiol level, increase in male-related genes and serum 11-ketotestosterone, ovarian regression, and spermatogonia proliferation were observed during plasmid feeding experiment. These results illustrate that amh overexpression plasmid feeding can induce a female-to-male transition in grouper.Summary Sentenceamh overexpression plasmid feeding can induce a female-to-male transition in grouper. |
| نوع الوثيقة: |
text |
| وصف الملف: |
text/HTML |
| اللغة: |
English |
| DOI: |
10.1093/biolre/ioy157 |
| الإتاحة: |
https://doi.org/10.1093/biolre/ioy157Test |
| حقوق: |
All rights reserved. |
| رقم الانضمام: |
edsbas.2101B150 |
| قاعدة البيانات: |
BASE |
