Complete remission of primary plasma cell leukemia with bortezomib, doxorubicin, and dexamethasone: a case report

التفاصيل البيبلوغرافية
العنوان: Complete remission of primary plasma cell leukemia with bortezomib, doxorubicin, and dexamethasone: a case report
المؤلفون: Chan, Steven M, George, Tracy, Cherry, Athena M, Medeiros, Bruno C
بيانات النشر: BioMed Central Ltd.
سنة النشر: 2009
المجموعة: BioMed Central
الوصف: Background Plasma cell leukemia (PCL) is a rare lymphoproliferative disorder considered to be a variant of multiple myeloma. It is an aggressive disease with a poor clinical response to standard chemotherapeutic agents. Case presentation A novel regimen consisting of bortezomib, doxorubicin, and dexamethasone is currently under active evaluation for the treatment of multiple myeloma. We employed this combination as front-line chemoinduction therapy for a case of primary PCL. Conclusion Complete remission was achieved with rapid normalization of hematologic parameters. The combination of bortezomib, doxorubicin and dexamethasone demonstrates promise in the treatment of PCL.
نوع الوثيقة: report
اللغة: English
العلاقة: http://www.casesjournal.com/content/2/1/121Test
الإتاحة: http://www.casesjournal.com/content/2/1/121Test
حقوق: Copyright 2009 Chan et al; licensee BioMed Central Ltd.
رقم الانضمام: edsbas.83FC6E14
قاعدة البيانات: BASE