التفاصيل البيبلوغرافية
| العنوان: |
Homing chemokines in rheumatoid arthritis |
| المؤلفون: |
Loetscher, Pius, Moser, Bernhard |
| بيانات النشر: |
BioMed Central Ltd. |
| سنة النشر: |
2002 |
| المجموعة: |
BioMed Central |
| مصطلحات موضوعية: |
BCA-1, chemokine receptors, chemokines, CXCR5, ectopic follicles |
| الوصف: |
In about 20% of patients with rheumatoid arthritis, B and T lymphocytes recruited into the inflamed synovium are organized into complex microstructures, which resemble secondary lymphoid organs. The development of such lymphoid aggregates with germinal centers appears to contribute to the pathogenesis of the disease. Growing evidence indicates that chemokines and their receptors control the recruitment and positioning of leukocytes as well as their organization into node-like lymphoid structures. Here, we comment on recent studies highlighting the importance of chemokines in rheumatoid arthritis, in particular of B-cell-activating chemokine-1 in lymphoid neogenesis in the inflamed synovium. |
| نوع الوثيقة: |
other non-article part of journal/newspaper |
| اللغة: |
English |
| العلاقة: |
http://arthritis-research.com/content/4/4/233Test |
| الإتاحة: |
http://arthritis-research.com/content/4/4/233Test |
| حقوق: |
Copyright 2002 BioMed Central Ltd |
| رقم الانضمام: |
edsbas.69499885 |
| قاعدة البيانات: |
BASE |
