التفاصيل البيبلوغرافية
| العنوان: |
From prescriptions to drug use periods - things to notice |
| المؤلفون: |
Tanskanen, Antti, Taipale, Heidi, Koponen, Marjaana, Tolppanen, Anna-Maija, Hartikainen, Sirpa, Ahonen, Riitta, Tiihonen, Jari |
| بيانات النشر: |
BioMed Central Ltd. |
| سنة النشر: |
2014 |
| المجموعة: |
BioMed Central |
| مصطلحات موضوعية: |
Prescription register, Modeling, Drug utilization, Pharmacoepidemiology |
| الوصف: |
Background Electronic prescription registers provide a vast data source for pharmacoepidemiological research. Prescriptions as such are not suitable for all research purposes; e.g., studying concurrent use of different drugs or adverse drug events during current use. For those purposes, data on dispensed prescriptions needs to be transformed to periods of drug use. Methods We used 3,828,292 dispensed prescriptions claimed between 1 January 2002 and 31 December 2009 for 28,093 persons with Alzheimer’s disease. Examples of drug use histories are presented to discuss different aspects that should be noticed when using register-based data consisting of drug purchases. Results There is no simple method for correctly transforming dispensed prescriptions to periods of drug use that is usable for all drugs and drug users. Fixed assumptions of daily dose (in defined daily doses, tablets or other units) and fixed time windows should be used with caution and adjusted for different drug use patterns. Conclusions We recommend that when transforming prescription drug purchases to drug use periods personal dose, purchasing pattern and other behavioral differences between patients should be taken into account. |
| نوع الوثيقة: |
other/unknown material |
| اللغة: |
English |
| العلاقة: |
http://www.biomedcentral.com/1756-0500/7/796Test |
| الإتاحة: |
http://www.biomedcentral.com/1756-0500/7/796Test |
| حقوق: |
Copyright 2014 Tanskanen et al.; licensee BioMed Central Ltd. |
| رقم الانضمام: |
edsbas.5E1EF86D |
| قاعدة البيانات: |
BASE |
