Protocol for a randomized comparison of integrated versus consecutive dual task practice in Parkinson’s disease: the DUALITY trial

التفاصيل البيبلوغرافية
العنوان: Protocol for a randomized comparison of integrated versus consecutive dual task practice in Parkinson’s disease: the DUALITY trial
المؤلفون: Strouwen, Carolien, Molenaar, Esther ALM, Keus, Samyra HJ, Münks, Liesbeth, Munneke, Marten, Vandenberghe, Wim, Bloem, Bastiaan R, Nieuwboer, Alice
بيانات النشر: BioMed Central Ltd.
سنة النشر: 2014
المجموعة: BioMed Central
مصطلحات موضوعية: Parkinson disease, Rehabilitation, Physical therapy, Neurologic gait disorder, Cognition, Dual task
الوصف: Background Multiple tasking is an integral part of daily mobility. Patients with Parkinson’s disease have dual tasking difficulties due to their combined motor and cognitive deficits. Two contrasting physiotherapy interventions have been proposed to alleviate dual tasking difficulties: either to discourage simultaneous execution of dual tasks (consecutive training); or to practice their concurrent use (integrated training). It is currently unclear which of these training methods should be adopted to achieve safe and consolidated dual task performance in daily life. Therefore, the proposed randomized controlled trial will compare the effects of integrated versus consecutive training of dual tasking (tested by combining walking with cognitive exercises). Methods and design Hundred and twenty patients with Parkinson’s disease will be recruited to participate in this multi-centered, single blind, randomized controlled trial. Patients in Hoehn & Yahr stage II-III, with or without freezing of gait, and who report dual task difficulties will be included. All patients will undergo a six-week control period without intervention after which they will be randomized to integrated or consecutive task practice. Training will consist of standardized walking and cognitive exercises delivered at home four times a week during six weeks. Treatment is guided by a physiotherapist twice a week and consists of two sessions of self-practice using an MP3 player. Blinded testers will assess patients before and after the control period, after the intervention period and after a 12-week follow-up period. The primary outcome measure is dual task gait velocity, i.e. walking combined with a novel untrained cognitive task to evaluate the consolidation of learning. Secondary outcomes include several single and dual task gait and cognitive measures, functional outcomes and a quality of life scale. Falling will be recorded as a possible adverse event using a weekly phone call for the entire study period. Discussion This randomized ...
نوع الوثيقة: report
اللغة: English
العلاقة: http://www.biomedcentral.com/1471-2377/14/61Test
الإتاحة: http://www.biomedcentral.com/1471-2377/14/61Test
حقوق: Copyright 2014 Strouwen et al.; licensee BioMed Central Ltd.
رقم الانضمام: edsbas.242A5D2D
قاعدة البيانات: BASE