التفاصيل البيبلوغرافية
العنوان: |
Mean Platelet Volume in Patients With Subclinical Hypothyroidism Attending at A Tertiary Care Hospital of Bangladesh |
المؤلفون: |
Hossain, Mohammad Afjal, Atiquzzaman, -, Sharifuzzaman, Mirza, Yasmin, Marufa, Siddiqui, Nazia Afrin, Amin, Farzana, Rahman, Mohammad Lutfar |
المصدر: |
Journal of Dhaka Medical College; Vol. 31 No. 1 (2022); 61-65 ; 2219-7494 ; 1028-0928 |
بيانات النشر: |
Dhaka Medical College Teachers' Association |
سنة النشر: |
2023 |
المجموعة: |
Bangladesh Journals Online (BanglaJOL) |
مصطلحات موضوعية: |
Subclinical hypothyroidism, mean platelet volume, thyroid stimulating hormone, free thyroxine |
الوقت: |
Bangladesh |
الوصف: |
Background: Subclinical hypothyroidism (SCH) is a common endocrine disorder affecting about 3-8% of the general population. On the other hand, mean platelet volume (MPV) is an indicator of platelet activity, and elevated MPV is associated with adverse cardio-metabolic complications. This study was conducted to observe MPV in SCH and to correlate it with thyroid-stimulating hormone (TSH) and free thyroxine (FT4) levels. Materials and Methods: This cross-sectional observational study was conducted in Medicine and Endocrinology OPD of US- Bangla Medical College & Hospital over twelve (12) months from September 2020 to August 2021. This study included forty (40) cases of newly detected SCH and twenty (20) age & body mass index (BMI) matched euthyroid control subjects as per inclusion and exclusion criteria. Results: SCH group had higher TSH and MPV than controls (P value <0.001 and <0.05 respectively) where age, BMI, and FT4 level were comparable (P value>0.05). MPV shows a positive correlation with BMI in SCH & controls (P values <0.05). MPV shows a significant positive correlation with TSH and a negative correlation with FT4 only in SCH (P<0.05) but not in controls (P value>0.05). Conclusion: Patients with SCH have elevated MPV, so they are at increased risk of developing an adverse cardiovascular outcome. J Dhaka Med Coll. 2022; 31(1) : 61-65 |
نوع الوثيقة: |
article in journal/newspaper |
وصف الملف: |
application/pdf |
اللغة: |
English |
العلاقة: |
https://www.banglajol.info/index.php/JDMC/article/view/65469/44374Test; https://www.banglajol.info/index.php/JDMC/article/view/65469Test |
الإتاحة: |
https://www.banglajol.info/index.php/JDMC/article/view/65469Test |
حقوق: |
Copyright (c) 2022 Journal of Dhaka Medical College |
رقم الانضمام: |
edsbas.7F2AED5A |
قاعدة البيانات: |
BASE |