دورية أكاديمية
Defining comprehensive biomarker-related testing and treatment practices for advanced non-small-cell lung cancer: Results of a survey of U.S. oncologists
| العنوان: | Defining comprehensive biomarker-related testing and treatment practices for advanced non-small-cell lung cancer: Results of a survey of U.S. oncologists |
|---|---|
| المؤلفون: | Mileham, Kathryn F, Schenkel, Caroline, Bruinooge, Suanna S, Freeman-Daily, Janet, Basu Roy, Upal, Moore, Amy, Smith, Robert A, Garrett-Mayer, Elizabeth, Rosenthal, Lauren, Garon, Edward B, Johnson, Bruce E, Osarogiagbon, Raymond U, Jalal, Shadia, Virani, Shamsuddin, Weber Redman, Mary, Silvestri, Gerard A |
| المصدر: | All Other Contributions |
| بيانات النشر: | Advocate Aurora Health Institutional Repository |
| سنة النشر: | 2022 |
| المجموعة: | Aurora Health Care Digital Repository |
| مصطلحات موضوعية: | United States, biomarkers, lung neoplasms, oncologists, Oncology |
| الوصف: | Background: An ASCO taskforce comprised of representatives of oncology clinicians, the American Cancer Society National Lung Cancer Roundtable (NLCRT), LUNGevity, the GO2 Foundation for Lung Cancer, and the ROS1ders sought to: characterize U.S. oncologists' biomarker ordering and treatment practices for advanced non-small-cell lung cancer (NSCLC); ascertain barriers to biomarker testing; and understand the impact of delays on treatment decisions. Methods: We deployed a survey to 2374 ASCO members, targeting U.S. thoracic and general oncologists. Results: We analyzed 170 eligible responses. For non-squamous NSCLC, 97% of respondents reported ordering tests for EGFR, ALK, ROS1, and BRAF. Testing for MET, RET, and NTRK was reported to be higher among academic versus community providers and higher among thoracic oncologists than generalists. Most respondents considered 1 (46%) or 2 weeks (52%) an acceptable turnaround time, yet 37% usually waited three or more weeks to receive results. Respondents who waited ≥3 weeks were more likely to defer treatment until results were reviewed (63%). Community and generalist respondents who waited ≥3 weeks were more likely to initiate non-targeted treatment while awaiting results. Respondents(42%, vs. 19% with ≥6 years of experience). Conclusions: Respondents reported high biomarker testing rates in patients with NSCLC. Treatment decisions were impacted by test turnaround time and associated with practice setting and physician specialization and experience. |
| نوع الوثيقة: | text |
| اللغة: | unknown |
| العلاقة: | https://institutionalrepository.aah.org/allother/87Test; https://xk8bg6rv9a.search.serialssolutions.com/?sid=Entrez:PubMed&id=pmid:34921524Test |
| DOI: | 10.1002/cam4.4459 |
| الإتاحة: | https://doi.org/10.1002/cam4.4459Test https://institutionalrepository.aah.org/allother/87Test https://xk8bg6rv9a.search.serialssolutions.com/?sid=Entrez:PubMed&id=pmid:34921524Test |
| رقم الانضمام: | edsbas.5972FB7 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/cam4.4459 |
|---|