دورية أكاديمية
Comprehensive Review and Update of Burning Eye Syndrome
| العنوان: | Comprehensive Review and Update of Burning Eye Syndrome |
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| المؤلفون: | Giacomazzi, Stephen, Urits, Ivan, Hoyt, Briggs, Hubble, Ashley, Cornett, Elyse M, Gress, Kyle, Charipova, Karina, Berger, Amnon A, Kassem, Hisham, Kaye, Alan D, Viswanath, Omar |
| المصدر: | Journal of Patient-Centered Research and Reviews |
| بيانات النشر: | Advocate Aurora Health Institutional Repository |
| سنة النشر: | 2021 |
| المجموعة: | Aurora Health Care Digital Repository |
| مصطلحات موضوعية: | burning mouth syndrome, neuropathy, ocular pain, chronic pain, lifitegrast, neuromodulation, Alternative and Complementary Medicine, Anesthesiology, Eye Diseases, Ophthalmology, Sense Organs, Therapeutics |
| الوصف: | Keratoconjunctivitis sicca (“dry eye”) is a common (14%–30% of adults over age 48) though difficult to treat condition that causes both discomfort and disability with associated dryness, pain, and visual disturbances. Etiology is not clearly understood but is likely varied, with a subset of patients suffering from chronic neuropathic pain referred to as “burning eye syndrome.” This review of existing literature summarizes the clinical presentation, natural history, pathophysiology, and treatment modalities of burning eye syndrome. Chronicity of burning eye syndrome is likely secondary to increased nociception from the cornea, decrease in inhibitory signals, and nerve growth factor expression alterations. Treatment centers around symptomatic alleviation and reduction of inflammation. Conservative treatments focus on well-being and perception and include exercise, acupuncture, and cognitive behavioral therapy. Topical treatment consists of the anti-adhesion T-cell antagonist lifitegrast, corticosteroids, and cyclosporine; all have moderate efficacy and good safety. Autologous serum eye drops are a second-line topical that may promote corneal and neural healing on top of symptomatic relief. When these treatments fail, patients may trial neuromodulation with transcranial magnetic stimulation. Despite general treatment safety, more research is needed to develop novel approaches to this condition, possibly focusing more directly on the neurological component. |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | unknown |
| العلاقة: | https://institutionalrepository.aah.org/jpcrr/vol8/iss3/5Test; https://institutionalrepository.aah.org/context/jpcrr/article/1813/viewcontent/Urits_REV.pdfTest |
| DOI: | 10.17294/2330-0698.1813 |
| الإتاحة: | https://doi.org/10.17294/2330-0698.1813Test https://institutionalrepository.aah.org/jpcrr/vol8/iss3/5Test https://institutionalrepository.aah.org/context/jpcrr/article/1813/viewcontent/Urits_REV.pdfTest |
| رقم الانضمام: | edsbas.318888A6 |
| قاعدة البيانات: | BASE |
| DOI: | 10.17294/2330-0698.1813 |
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