دورية أكاديمية
Understanding hyper-reflexia in acute motor axonal neuropathy (AMAN)
| العنوان: | Understanding hyper-reflexia in acute motor axonal neuropathy (AMAN) |
|---|---|
| المؤلفون: | Versace V., Campostrini S., Rastelli E., Sebastianelli L., Nardone R., Pucks-Faes E., Saltuari L., Kofler M., Uncini A. |
| المساهمون: | Versace, V., Campostrini, S., Rastelli, E., Sebastianelli, L., Nardone, R., Pucks-Faes, E., Saltuari, L., Kofler, M., Uncini, A. |
| سنة النشر: | 2020 |
| المجموعة: | ARUd'A - Archivio Istituzionale della ricerca dell'università Chieti-Pescara (IRIS) |
| مصطلحات موضوعية: | Acute motor axonal neuropathy, Central motor conduction time, Guillain-Barré syndrome, Hyper-reflexia, Presynaptic inhibition, Reciprocal inhibition |
| الوصف: | Hyper-reflexia is occasionally seen in acute motor axonal neuropathy (AMAN), but its pathophysiology is unclear. We report a patient with AMAN following Campylobacter jejuni enteritis, who showed generalized hyper-reflexia, bilateral Hoffmann sign and right Babinski sign. MRI and transcranial magnetic stimulation of the motor cortex disclosed no corticospinal tract involvement. An extensive electrophysiological investigation documented α-motoneuron hyperexcitability and dysfunction of the interneuronal inhibitory circuits in the spinal anterior horn. We propose an immune-mediated damage of the spinal inhibitory interneuronal network as possible mechanism inducing hyper-reflexia in AMAN. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | STAMPA |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/32595063; info:eu-repo/semantics/altIdentifier/wos/WOS:000552126100001; volume:50; issue:3; firstpage:139; lastpage:144; numberofpages:6; journal:NEUROPHYSIOLOGIE CLINIQUE-CLINICAL NEUROPHYSIOLOGY; http://hdl.handle.net/11564/734524Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85086930081; https://www.sciencedirect.com/science/article/pii/S0987705320300563Test |
| DOI: | 10.1016/j.neucli.2020.05.004 |
| الإتاحة: | https://doi.org/10.1016/j.neucli.2020.05.004Test http://hdl.handle.net/11564/734524Test https://www.sciencedirect.com/science/article/pii/S0987705320300563Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.BD13DD10 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.neucli.2020.05.004 |
|---|