دورية أكاديمية
Procedural and 30-day clinical outcomes following transcatheter aortic valve replacement with lotus valve: Results of the RELEVANT study
| العنوان: | Procedural and 30-day clinical outcomes following transcatheter aortic valve replacement with lotus valve: Results of the RELEVANT study |
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| المؤلفون: | Montone, Rocco A, Testa, Luca, Fraccaro, Chiara, Montorfano, Matteo, Castriota, Fausto, Nerla, Roberto, Tusa, Maurizio, Giannini, Francesco, Garatti, Andrea, Tarantini, Giuseppe, PETRONIO, ANNA, Brambilla, Nedy, Bedogni, Francesco, ANGELILLIS, MARCO |
| المساهمون: | Montone, Rocco A, Testa, Luca, Fraccaro, Chiara, Montorfano, Matteo, Castriota, Fausto, Nerla, Roberto, Angelillis, Marco, Tusa, Maurizio, Giannini, Francesco, Garatti, Andrea, Tarantini, Giuseppe, Petronio, Anna, Brambilla, Nedy, Bedogni, Francesco |
| سنة النشر: | 2017 |
| المجموعة: | ARPI - Archivio della Ricerca dell'Università di Pisa |
| مصطلحات موضوعية: | Aortic valve disease, Percutaneous intervention, Structural heart disease intervention, Transcatheter valve implantation, Radiology, Nuclear Medicine and Imaging, Cardiology and Cardiovascular Medicine |
| الوصف: | Objectives: We report procedural and 30-day clinical outcomes following transcatheter aortic valve replacement (TAVR) with Lotus Valve system in a high-risk population. Background: Lotus valve is a second-generation TAVR fully repositionable and retrievable device. RELEVANT (REgistry of Lotus valvE for treatment of aortic VAlve steNosis with Tavr) study is an Italian prospective multicentre registry. Methods: Five major centers performing TAVR using Lotus participated. All high-risk symptomatic patients with severe aortic stenosis were evaluated by a heart team and screened for eligibility for TAVR. Primary end-points were procedural and 30-day mortality. Secondary endpoints included procedural and 30-day safety/effectiveness metrics according to Valve Academic Research Consortium (VARC)-2 criteria. Results: Two hundred and twenty-five patients undergoing TAVR with Lotus were enrolled. Mean age was 82.6±6.3 years, 51.6% females. Mean STS score for mortality was 8.3±5.6. Procedural success was achieved in 98.7% of patients. All-cause mortality was 2.2% at discharge and 2.7% at 30-day. Stroke rate was 2.2% at discharge and 3.1% at 30-day. Patients requiring a new permanent pacemaker implantation were 30.7% at discharge and 31.8% at 30-day. Paravalvular regurgitation (PVR) was trace/mild in 99.1% of patients at discharge. Only two patients (0.9%) had moderate PVR at discharge and at 30-day, whereas none had severe PVR. Conclusions: RELEVANT study showed that TAVR using Lotus, in a real-world population of patients with severe aortic stenosis at high surgical risk, was associated with excellent device success implantation and early safety according to VARC-2 definition. The pacemaker implantation rate was about a third of patients. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | ELETTRONICO |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/28145039; journal:CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS; http://hdl.handle.net/11568/847850Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85011310371; http://onlinelibrary.wiley.com/journal/10.1002Test/(ISSN)1522-726X |
| DOI: | 10.1002/ccd.26914 |
| DOI: | 10.1002/(ISSN)1522-726X |
| الإتاحة: | https://doi.org/10.1002/ccd.26914Test http://hdl.handle.net/11568/847850Test |
| رقم الانضمام: | edsbas.D0664FFC |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/ccd.26914 |
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