دورية أكاديمية
Surgical complications after pancreas transplantation with portal-enteric drainage
| العنوان: | Surgical complications after pancreas transplantation with portal-enteric drainage |
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| المؤلفون: | Reddy, K. S., Stratta, R. J., Shokouh Amiri, M. H., Alloway, R., Gaber, A. O., EGIDI, MARIA FRANCESCA |
| المساهمون: | Reddy, K. S., Stratta, R. J., Shokouh Amiri, M. H., Alloway, R., Egidi, MARIA FRANCESCA, Gaber, A. O. |
| سنة النشر: | 1999 |
| المجموعة: | ARPI - Archivio della Ricerca dell'Università di Pisa |
| مصطلحات موضوعية: | Adult, Antibiotic Prophylaxi, Anticoagulant, Diabetes Mellitus, Type 1, Drainage, Female, Graft Survival, Human, Immunosuppressive Agent, Incidence, Male, Middle Aged, Pancreas Transplantation, Reoperation, Retrospective Studie, Postoperative Complications |
| الوصف: | BACKGROUND: Despite recent advances, surgical complications remain an important source of morbidity after pancreas transplantation (PTX). Several previous studies have delineated the surgical complications after PTX with systemic-bladder (S-B) drainage, but data are limited regarding the incidence and outcomes of surgical complications after PTX with portal-enteric (P-E) drainage. STUDY DESIGN: We retrospectively studied surgical complications after 83 vascularized PTXs with P-E drainage in 79 patients (65 simultaneous kidney-PTXs [SKPT] and 18 solitary PTXs [SPT], 8 pancreas alone and 10 pancreas after kidney transplantation). Twelve (15%) were retransplants. A surgical complication was defined as the need for repeat laparotomy within the first 3 months after PTX. RESULTS: A total of 53 surgical complications requiring repeat laparotomy occurred in 31 patients (37%). The incidence of surgical complications in SKPT and SPT was 38% and 33%, respectively. The most common indications for repeat laparotomy were: vascular thrombosis in 13% (SKPT 14% and SPT 11%), intraabdominal infection in 10% (SKPT 12% and SPT 0%), intraabdominal bleeding in 8% (SKPT 8% and SPT 11%), and duodenal allograft leak in 4% (SKPT 3% and SPT 6%). Patient survival rates at 1 and 3 years with versus without surgical complications were 84% and 80% versus 94% and 86%, respectively (p = NS). Pancreas graft survival rates at 1 and 3 years with versus without surgical complications were 48% and 44% versus 89% and 76%, respectively (p < 0.0001). The incidence of surgical complications was 45% in the first 42 P-E transplantations performed between 1990 and 1995, compared with 29% in the next 41 transplantations performed during 1996 and 1997 (p = NS). The mean number of repeat laparotomies per patient decreased from 1.2 in the former group to 0.5 in the latter group (p = NS). The incidence rates of vascular thrombosis, intraabdominal infection, and duodenal leak in the former and latter groups were 17% versus 10%, 12% versus 7%, and 2% versus ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | STAMPA |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/10472932; info:eu-repo/semantics/altIdentifier/wos/WOS:000082238700011; volume:189; issue:3; firstpage:305; lastpage:313; numberofpages:9; journal:JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS; http://hdl.handle.net/11568/872235Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-0032821390; http://www.sciencedirect.com/science/article/pii/S1072751599001350Test |
| DOI: | 10.1016/S1072-7515(99)00135-0 |
| الإتاحة: | https://doi.org/10.1016/S1072-7515Test(99)00135-0 http://hdl.handle.net/11568/872235Test http://www.sciencedirect.com/science/article/pii/S1072751599001350Test |
| رقم الانضمام: | edsbas.8BBF13C1 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/S1072-7515(99)00135-0 |
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