دورية أكاديمية
Osteochondral alteration in a child treated with levetiracetam
| العنوان: | Osteochondral alteration in a child treated with levetiracetam |
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| المؤلفون: | Turati, Marco, Glard, Yann, Afonso, David, Griffet, Jacques, Bigoni, Marco |
| المساهمون: | Service de chirurgie pédiatrique CHU Grenoble, Centre Hospitalier Universitaire CHU Grenoble (CHUGA), Service de Chirurgie orthopédique et traumatologie, Hôpital d'Instruction des Armées Legouest, Service de Santé des Armées-Service de Santé des Armées, Hôpital Saint-Joseph Marseille, Santé, Plasticité, Motricité (TIMC-IMAG-SPM), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes 2016-2019 (UGA 2016-2019 )-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes 2016-2019 (UGA 2016-2019 ), Università degli Studi di Milano-Bicocca = University of Milano-Bicocca (UNIMIB) |
| المصدر: | ISSN: 1060-152X ; Journal of Pediatric Orthopaedics B ; https://hal.science/hal-02069156Test ; Journal of Pediatric Orthopaedics B, 2017, 26 (2), pp.189-192. ⟨10.1097/BPB.0000000000000354⟩. |
| بيانات النشر: | HAL CCSD Lippincott, Williams & Wilkins |
| سنة النشر: | 2017 |
| المجموعة: | Archive ouverte du Service de Santé des Armées (HAL) |
| مصطلحات موضوعية: | MESH: Analgesics, MESH: Anticonvulsants, MESH: Pediatrics, MESH: Piracetam, MESH: Range of Motion, Articular, MESH: Talus, MESH: Weight-Bearing, MESH: Braces, MESH: Child, MESH: Conservative Treatment, MESH: Female, MESH: Humans, MESH: Levetiracetam, MESH: Magnetic Resonance Imaging, MESH: Osteochondritis Dissecans, [SDV]Life Sciences [q-bio], [SCCO.NEUR]Cognitive science/Neuroscience |
| الوصف: | International audience ; Levetiracetam is a relatively novel antiepileptic drug used for the treatment of partial and generalized seizures in adult and children. Several animal studies describe a possible drug adverse effect on skeletal growth and metabolism. We present a case report of a 10-year-old female child who underwent a prolonged 7-year treatment with levetiracetam for sporadic secondary convulsions secondary to enterovirus encephalitis at the age of 15 months. This patient developed an osteochondritis dissecans lesion (OCD) of the talar head well treated conservatively. Only a few cases have been described of this rare type of OCD. We hypothesize a possible association between levetiracetam therapy and OCD development, suggesting the importance of long-term control of bone growth in levetiracetam-treated pediatric populations. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/27341121; hal-02069156; https://hal.science/hal-02069156Test; PUBMED: 27341121 |
| DOI: | 10.1097/BPB.0000000000000354 |
| الإتاحة: | https://doi.org/10.1097/BPB.0000000000000354Test https://hal.science/hal-02069156Test |
| رقم الانضمام: | edsbas.CF6B2E03 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1097/BPB.0000000000000354 |
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