دورية أكاديمية
The IHAT-GUT Iron Supplementation Trial in Rural Gambia: Barriers, Facilitators, and Benefits.
| العنوان: | The IHAT-GUT Iron Supplementation Trial in Rural Gambia: Barriers, Facilitators, and Benefits. |
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| المؤلفون: | Stelle, Isabella, McDonagh, Lorraine K, Hossain, Ilias, Kalea, Anastasia Z, Pereira, Dora IA |
| بيانات النشر: | MDPI AG //dx.doi.org/10.3390/nu13041140 Nutrients |
| سنة النشر: | 2021 |
| المجموعة: | Apollo - University of Cambridge Repository |
| مصطلحات موضوعية: | anaemia, clinical trial, global health, iron, iron deficiency, iron deficiency anaemia, low resource setting, malnutrition, micronutrients, nutrition intervention, public health, qualitative, Anemia, Iron-Deficiency, Child, Delivery of Health Care, Dietary Supplements, Double-Blind Method, Ferric Compounds, Focus Groups, Gambia, Humans, Dietary, Poverty, Qualitative Research, Rural Population |
| الوصف: | INTRODUCTION: In most sub-Saharan African countries iron deficiency anaemia remains highly prevalent in children and this has not changed in the last 25 years. Supplementation with iron hydroxide adipate tartrate (IHAT) was being investigated in anaemic children in a phase two clinical trial (termed IHAT-GUT), conducted at the Medical Research Council Unit the Gambia at the London School of Hygiene and Tropical Medicine (LSHTM) (abbreviated as MRCG hereof). This qualitative study aimed to explore the personal perceptions of the trial staff in relation to conducting a clinical trial in such settings in order to highlight the health system specific needs and strengths in the rural, resource-poor setting of the Upper River Region in the Gambia. METHODS: Individual interviews (n = 17) were conducted with local trial staff of the IHAT-GUT trial. Data were analysed using inductive thematic analysis. RESULTS: Potential barriers and facilitators to conducting this clinical trial were identified at the patient, staff, and trial management levels. Several challenges, such as the rural location and cultural context, were identified but noted as not being long-term inhibitors. Participants believed the facilitators and benefits outnumbered the barriers, and included the impact on education and healthcare, the ambitious and knowledgeable locally recruited staff, and the local partnership. CONCLUSIONS: While facilitators and barriers were identified to conducting this clinical trial in a rural, resource-poor setting, the overall impact was perceived as beneficial, and this study is a useful example of community involvement and partnership for further health improvement programs. To effectively implement a nutrition intervention, the local health systems and context must be carefully considered through qualitative research beforehand. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text/xml; application/zip; application/pdf |
| اللغة: | English |
| العلاقة: | https://www.repository.cam.ac.uk/handle/1810/319426Test |
| DOI: | 10.17863/CAM.66549 |
| الإتاحة: | https://doi.org/10.17863/CAM.66549Test https://www.repository.cam.ac.uk/handle/1810/319426Test |
| رقم الانضمام: | edsbas.470DB038 |
| قاعدة البيانات: | BASE |
| DOI: | 10.17863/CAM.66549 |
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