دورية أكاديمية
Comparison of the Effectiveness and Safety of Intense Pulsed Light (IPL) and Placebo Versus Intense Pulsed Light and Eflornithine in Idiopathic Facial Hirsutism
| العنوان: | Comparison of the Effectiveness and Safety of Intense Pulsed Light (IPL) and Placebo Versus Intense Pulsed Light and Eflornithine in Idiopathic Facial Hirsutism |
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| المؤلفون: | Janjua, Fauzia Khalid, Shaukat, Shehla, Afzal, Amina, Zahoor, Mahwish, Rafat, Maryam, Butt, Ghazala, Nadeem, Muhammad, Kazmi, Atif Hasnain |
| المصدر: | Annals of King Edward Medical University; Vol. 26 No. 3 (2020): AKEMU; 515-520 ; 2079-0694 ; 2079-7192 ; 10.21649/akemu.v26i3 |
| بيانات النشر: | King Edward Medical University |
| سنة النشر: | 2020 |
| المجموعة: | Annals of King Edward Medical University |
| مصطلحات موضوعية: | Eflornithine, Intense pulsed light, Hirsutism |
| الوصف: | Background: Hirsutism is a distressing condition among women and one of the major causes of depression. Objective: To compare the effectiveness and safety of Eflornithine and Intense Pulsed Light versus Intense pulsed light and Placebo in idiopathic facial hirsutism. Methods: In this randomized placebo-controlled trial, 40 female patients of >18 years, suffering from idiopathic facial hirsutism with Fitzpatrick skin type III and IV, were included. Two groups, A and B were made. A-Group (right side of all patients) was treated with Intense Pulsed Light (IPL) and placebo and Group B (left side of all patients) with Intense Pulsed Light (IPL) and Eflornithine. Six sessions (each with 4-week interval) were done for both treatment modalities. Before first session and 4 weeks after the last session photographs were taken and hair count and hair reduction were calculated. Results: In Group A (Intense Pulsed Light (IPL) and Placebo) treated sites effectiveness of treatment was seen in 22 (55%) while in Group B (Intense Pulsed Light (IPL) and Eflornithine) treated sites effectiveness was seen in 35 (87.5%). This proved that efficacy of Group B treatment was higher than Group A (p-value=0.001). Earlier side effects like mild transient erythema, transient swelling and transient pain were seen with Intense Pulsed Light (IPL) in 100% of the patients and late side effects in both groups like folliculitis (p-value=0.692) and hyperpigmentation (p-value=0.064) were also recorded and compared. Conclusion: Intense Pulsed Light (IPL) and Eflornithine combination is more successful than Intense Pulsed Light (IPL) and Placebo for the treatment of idiopathic facial hirsutism. Both treatments were equally safe. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | http://annalskemu.org/journal/index.php/annals/article/view/4155/2431Test; http://annalskemu.org/journal/index.php/annals/article/view/4155Test |
| DOI: | 10.21649/akemu.v26i3.4155 |
| الإتاحة: | https://doi.org/10.21649/akemu.v26i3.4155Test https://doi.org/10.21649/akemu.v26i3Test http://annalskemu.org/journal/index.php/annals/article/view/4155Test |
| حقوق: | http://creativecommons.org/licenses/by/4.0Test |
| رقم الانضمام: | edsbas.1D91BA72 |
| قاعدة البيانات: | BASE |
| DOI: | 10.21649/akemu.v26i3.4155 |
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