دورية أكاديمية

Clinical analysis of treatment outcomes in women with infertility against the background of polycystic ovaries syndrome and chronic endometritis

التفاصيل البيبلوغرافية
العنوان: Clinical analysis of treatment outcomes in women with infertility against the background of polycystic ovaries syndrome and chronic endometritis
المؤلفون: Khmil Doswald, A., Malanchuk, L.
المصدر: Journal of Education, Health and Sport; Tom 11 Nr 9 (2021); 908-922 ; Journal of Education, Health and Sport; Vol. 11 No. 9 (2021); 908-922 ; 2391-8306
بيانات النشر: Nicolaus Copernicus University, Toruń, Poland
سنة النشر: 2021
المجموعة: Akademicka Platforma Czasopism
مصطلحات موضوعية: PCOS, chronic endometritis, infertility, endometrium, histology, anovulation, hysteroscopy, PRP-therapy of the endometrium, lipid infusions, cryocycle, NC, ET, HRT, ART, COS
الوصف: Introduction. In women with polycystic ovary syndrome, infertility is a serious and urgent problem, which is caused not only by anovulatory menstrual cycles [1], but also by changes in the histological structure of the endometrium, which adversely affects embryo implantation and subsequent pregnancy. Thus, chronic endometritis and polycystic ovary syndrome are among the causative factors of repeated unsuccessful embryo implantation in assisted reproductive technology (ART) programs [2-3]. Aim of the study. To analyze the clinical outcomes of patients with infertility against the background of PCOS and chronic endometritis (CE) in ART protocols, depending on the treatment scheme. Materials, methods and their discussion. The study included 140 patients with infertility against the background of PCOS and CE. Study group I comprised 43 patients with PCOS and CE, who were offered conventional treatment for chronic endometritis. Study group II comprised 63 patients with PCOS and CE, who were treated using a modified scheme that additionally included alpha-lipoic acid, endometrial plasma therapy and lipid infusions (to reduce cytotoxicity) on the day of frozen embryo transfer (FET). In both groups, delayed embryo transfer was performed in cryocycles after 2-4 months. Cryoprotocols were performed using HRT and in the NC. The control group comprised 35 women with infertility due to male causes. Results and discussion. Comparing causes of infertility in the patients with PCOS and CE, we found no significant differences between the study groups. There was no significant difference between the study groups and the control group in the frequency of surgical interventions in the anamnesis of the patients. It should be noted, however, that the structure of surgical interventions in the first and second study groups was dominated by the IUDs (respectively, in 18.60% and 19.35% of the cases) relative to the control group (2.86%). The anamnesis records of the patients show no significant differences between both study groups in ...
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: English
العلاقة: https://apcz.umk.pl/JEHS/article/view/38152/32100Test; https://apcz.umk.pl/JEHS/article/view/38152Test
الإتاحة: https://apcz.umk.pl/JEHS/article/view/38152Test
حقوق: Prawa autorskie (c) 2021 A. Khmil Doswald, L. Malanchuk ; http://creativecommons.org/licenses/by-nc-sa/4.0Test
رقم الانضمام: edsbas.43188847
قاعدة البيانات: BASE